Evidence map›Paper›PMID 34819882›Full record

ArticleFrontiers in psychiatry2021

A Longitudinal Study of Parent-Child Interactions and Language Outcomes in Fragile X Syndrome and Other Neurodevelopmental Disorders.

Lauren Bush, Gary E Martin, Emily Landau, Molly Losh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The impact of individual factors on linguistic alignment of autistic boys and their mothers.Autism : the international journal of research and practice · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lauren BushRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, United States.
Gary E MartinDepartment of Communication Sciences and Disorders, St. John's University, Staten Island, NY, United States.
Emily LandauRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, United States.
Molly LoshRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, United States.
Northwestern University · USRush University Medical Center · USSt. John's University · US

Funding

UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PIVEN, JOSEPH · 1985 to 2012
$28.7M
A Family-Genetic Study of Autism and Fragile X SyndromeR01MH091131 · NIMH · NORTHWESTERN UNIVERSITY · PI Molly C Losh · 2012 to 2026
$10.1M
A Family-Genetic Study of Language in AutismR01DC010191 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Molly C Losh · 2010 to 2026
$7.8M
Pragmatic Skills of Young Males and Females with Fragile X SyndromeR01HD038819 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARTIN, GARY EVERETT · 2001 to 2011
$4.2M
Speech of Young Males with Fragile X SyndromeR01HD044935 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZAJAC, DAVID J · 2003 to 2012
$4.0M
NICHD NIH HHS P30 HD003110NICHD NIH HHS R01 HD038819NICHD NIH HHS R01 HD044935NIDCD NIH HHS R01 DC010191NIMH NIH HHS R01 MH091131
6 · The paper itself

Abstract

Difficulties with pragmatic language (i.e., language in social contexts, such as conversational ability) are a noted characteristic of the language profiles of both fragile X syndrome (FXS) and autism spectrum disorder (ASD), conditions which show significant phenotypic overlap. Understanding the origins and developmental course of pragmatic language problems in FXS and other developmental conditions associated with language impairment is a critical step for the development of targeted interventions to promote communicative competence across the lifespan. This study examined pragmatic language in the context of parent-child interactions in school-age children with FXS (who did and did not meet ASD criteria on the ADOS;

Indexed as

autism spectrum disorderbroad autism phenotypefragile X syndromelongitudinal outcomesparent-child interactionpragmatic languagesocial communication

Identifiers

PMID34819882
PMCPMC8606641
OpenAlexW3212748929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.