Evidence map›Paper›PMID 34819877›Full record

ReviewFrontiers in physiology2021

Calcium-Dependent Ion Channels and the Regulation of Arteriolar Myogenic Tone.

William F Jackson

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Loss of cerebral autoregulation drives abnormal perfusion patterns after stroke.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
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  6. Coronary Spasm Due to Pulsed Field Ablation: A State-of-the-Art Review.Pacing and clinical electrophysiology : PACE · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Niclosamide potentiates TMEM16A and induces vasoconstriction.The Journal of general physiology · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Cracking the Endothelial Calcium (CaInternational journal of molecular sciences · 2023
    Review
  17. Review
  18. [Research progress of chondrocyte mechanotransduction mediated by TRPV4 and PIEZOs].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
  19. Functional cooperation between IKCell proliferation · 2023
    Article
  20. Vascular mechanotransduction.Physiological reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

William F JacksonDepartment of Pharmacology and Toxicology, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, United States.
Michigan State University · US

Funding

SIGNALING MECHANISMS IN ARTERIES AND VEINS IN HYPERTENSIONP01HL070687 · NHLBI · MICHIGAN STATE UNIVERSITY · PI FINK, GREGORY D · 2003 to 2019
$22.8M
Cerebral parenchymal arteriole dysfunction and cognitive decline in a life-long high fat feeding modelR01HL137694 · NHLBI · MICHIGAN STATE UNIVERSITY · PI DORRANCE, ANNE M., JACKSON, WILLIAM F. · 2017 to 2020
$2.1M
NHLBI NIH HHS P01 HL070687NHLBI NIH HHS R01 HL137694
6 · The paper itself

Abstract

Arterioles in the peripheral microcirculation regulate blood flow to and within tissues and organs, control capillary blood pressure and microvascular fluid exchange, govern peripheral vascular resistance, and contribute to the regulation of blood pressure. These important microvessels display pressure-dependent myogenic tone, the steady state level of contractile activity of vascular smooth muscle cells (VSMCs) that sets resting arteriolar internal diameter such that arterioles can both dilate and constrict to meet the blood flow and pressure needs of the tissues and organs that they perfuse. This perspective will focus on the Ca

Indexed as

arteriolescalcium ionsendothelial cellsion channelsmicrocirculationvascular smooth muscle

Identifiers

PMID34819877
PMCPMC8607693
OpenAlexW3212391143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.