Evidence map›Paper›PMID 34819856›Full record

ArticleFrontiers in pharmacology2021

Biomineralized Composite Liquid Crystal Fiber Scaffold Promotes Bone Regeneration by Enhancement of Osteogenesis and Angiogenesis.

Yi Zhan, Bing Deng, Huixian Wu, Changpeng Xu, Ruiying Wang, Wenqiang Li, Zhixiong Pan

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yi ZhanDepartment of Orthopedic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Bing DengDepartment of Orthopedic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Huixian WuDepartment of Orthopedic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Changpeng XuDepartment of Orthopaedics, Guangdong Second Provincial General Hospital, Guangzhou, China.
Ruiying WangDepartment of Orthopedic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Wenqiang LiEngineering Technology Research Center for Sports Assistive Devices of Guangdong, Guangzhou Sport University, Guangzhou, China.
Zhixiong PanDepartment of Orthopedic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid crystals (LCs) are appealing biomaterials for applications in bone regenerative medicine due to their tunable physical properties and anisotropic viscoelastic behavior. This study reports a novel composite poly (L-lactide) (PLLA) scaffold that is manufactured by a simple electrospinning and biomineralization technique that precisely controls the fibrous structure in liquid LC phase. The enriched-LC composites have superior mineralization ability than neat PLLA; furthermore BMSC cells were inoculated onto the HAP-PLLA/LC with hydroxyapatite (HAP) composite scaffold to test the capability for osteogenesis

Indexed as

biomimetic mineralizationliquid crystal fiberosteogenic differentiationregenerationvascularization

Identifiers

PMID34819856
PMCPMC8606401

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.