Evidence map›Paper›PMID 34819848›Full record

ArticleFrontiers in aging neuroscience2021

Aberrant Changes in Cortical Complexity in Right-Onset Versus Left-Onset Parkinson's Disease in Early-Stage.

Lin Zhang, Qin Shen, Haiyan Liao, Junli Li, Tianyu Wang, Yuheng Zi, Fan Zhou, Chendie Song, Zhenni Mao, Min Wang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lin ZhangDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Qin ShenDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Haiyan LiaoDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Junli LiDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Tianyu WangDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yuheng ZiDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Fan ZhouDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Chendie SongDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Zhenni MaoDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Min WangDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Sainan CaiDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Changlian TanDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Second Xiangya Hospital of Central South University · CNCentral South University · CNHangzhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing evidence to show that motor symptom lateralization in Parkinson's disease (PD) is linked to non-motor features, progression, and prognosis of the disease. However, few studies have reported the difference in cortical complexity between patients with left-onset of PD (LPD) and right-onset of PD (RPD). This study aimed to investigate the differences in the cortical complexity between early-stage LPD and RPD. High-resolution T1-weighted magnetic resonance images of the brain were acquired in 24 patients with LPD, 34 patients with RPD, and 37 age- and sex-matched healthy controls (HCs). Cortical complexity including gyrification index, fractal dimension (FD), and sulcal depth was analyzed using surface-based morphometry

Indexed as

cortical complexitylateralityParkinson’s diseaseside-of-onsetsurface-based morphometry

Identifiers

PMID34819848
PMCPMC8606890
OpenAlexW3211658350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.