Evidence map›Paper›PMID 34819826›Full record

ArticleEJIFCC2021

In-House Algorithm for Reporting Discrepant HbA1c Result and Troubleshooting a Case of False Low HbA1c.

Vivek Pant, Abha Shrestha, Devish Pyakurel, Keyoor Gautam, Santosh Pradhan

Open access · greenAbstract read
In one paragraph

Article in EJIFCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vivek PantDepartment of Clinical Biochemistry, Samyak Diagnostic, Jawalakhel, Lalitpur, Nepal.
Abha ShresthaDepartment of Pathology, Samyak Diagnostic, Jawalakhel, Lalitpur, Nepal.
Devish PyakurelDepartment of Pathology, Samyak Diagnostic, Jawalakhel, Lalitpur, Nepal.
Keyoor GautamDepartment of Pathology, Samyak Diagnostic, Jawalakhel, Lalitpur, Nepal.
Santosh PradhanDepartment of Clinical Biochemistry, Samyak Diagnostic, Jawalakhel, Lalitpur, Nepal.
Nepal Development Research Institute · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an unusual case of a patient having low glycosylated hemoglobin (HbA1c) below the reportable range, despite having borderline fasting blood glucose. The patient had decreased erythrocytes count and elevated reticulocyte count, with no evidence of hemoglobinopathy. He reported taking multidrug therapy for borderline lepromatous leprosy. Dapsone induced hemolysis was identified as the cause for the discordant HbA1c. Thus, it is important to be aware of medications and conditions that may lead to a falsely low HbA1c level so that incorrect treatment decisions are not made. In such situations, alternative measure of glycemic control, such as fructosamine is recommended. Further it is also recommended that clinical laboratories have standard protocol to troubleshoot any discrepant HbA1c result.

Indexed as

Bio-Rad D-10 HPLCdiscrepant HbA1cfalse low HbA1chigh performance liquid chromatography (HPLC)

Identifiers

PMID34819826
PMCPMC8592636
OpenAlexW3216431294

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.