ArticleNature microbiology2021
Protective role of the Arabidopsis leaf microbiota against a bacterial pathogen.
Article in Nature microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 81 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.
- How Useful Are Plant Traits in Explaining Variation in Phyllosphere Microbial Abundance and Composition Across Hosts?Environmental microbiology · 2025Pooled it
- Review
- Article
- Metabolic feedbacks drive population dynamics and can lead to oscillations among leaf bacteria.Nature communications · 2026Article
- A defined community of core gut microbiota members promotes cognitive performance in honey bees.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Associations between phloem microbiota and metabolomes in three North American ash species (Fraxinus spp.) susceptible to emerald ash borer (Agrilus planipennis).Environmental microbiome · 2026Article
- Specialization of independently acquired flagellar FliC proteins in plant-associatedProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Specialization of independently acquired flagellar FliC proteins in plant-associatedbioRxiv : the preprint server for biology · 2026Article
- The plant microbiota: From theoretical advances to applications.Fundamental research · 2026Review
- Mechanistic Insights for Microbiome Application in Plant Disease Resistance.Molecular plant pathology · 2026Review
- Beyond the Single Isolate: Leveraging Plant-Associated Microbial Communities for Crop Resilience.Microorganisms · 2026Review
- Article
- Diverse rhizospheric Bacillus are required for protection against a leaf pathogen.The ISME journal · 2026Article
- A field-based study of phyllosphere mycobiomes in apple orchards under varying agricultural management strategies.ISME communications · 2026Article
- Different fungal and bacterial pathogen infections alter the grapevine microbiome and phenolic profiles in a localized and specific manner.Frontiers in plant science · 2026Article
- Disease-induced changes inFrontiers in microbiology · 2026Article
- Distinct and Intermediate Bacterial Community Structure of the Wasabi Rhizome Based on Compartment-resolved 16S rRNA Gene Profiling.Microbes and environments · 2026Article
- Article
- Investigating the Involvement of Target Protein in Plant-Pathogen Interactions Through Ectopic Expression in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Cold-tolerant bacteria from alpine Rosaceae plants modulate transcriptional responses of apple and strawberry plantlets to freezing stress.Frontiers in plant science · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The aerial parts of plants are host to taxonomically structured bacterial communities. Members of the core phyllosphere microbiota can protect Arabidopsis thaliana against foliar pathogens. However, whether plant protection is widespread and to what extent the modes of protection differ among phyllosphere microorganisms are not clear. Here, we present a systematic analysis of plant protection capabilities of the At-LSPHERE, which is a collection of >200 bacterial isolates from A. thaliana, against the bacterial pathogen Pseudomonas syringae pv. tomato DC3000. In total, 224 bacterial leaf isolates were individually assessed for plant protection in a gnotobiotic system. Protection against the pathogen varied, with ~10% of leaf microbiota strains providing full protection, ~10% showing intermediate levels of protection and the remaining ~80% not markedly reducing disease phenotypes upon infection. The most protective strains were distributed across different taxonomic groups. Synthetic community experiments revealed additive effects of strains but also that a single strain can confer full protection in a community context. We also identify different mechanisms that contribute to plant protection. Although pattern-triggered immunity coreceptor signalling is involved in protection by a subset of strains, other strains protected in the absence of functional plant immunity receptors BAK1 and BKK1. Using a comparative genomics approach combined with mutagenesis, we reveal that direct bacteria-pathogen interactions contribute to plant protection by Rhizobium Leaf202. This shows that a computational approach based on the data provided can be used to identify genes of the microbiota that are important for plant protection.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.