ArticleScientific reports2021
Sex differences in auditory processing vary across estrous cycle.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- The Influence of Sex, Ear, and Age on Auditory Brainstem Responses Recorded with the NeuroAudio System.Diagnostics (Basel, Switzerland) · 2026Article
- Gonadal and sex chromosomal contributions to sex differences in mammalian brain organization.bioRxiv : the preprint server for biology · 2026Article
- Large-scale multi-site study shows no association between musical training and early auditory neural sound encoding.Nature communications · 2025Article
- Gender effect on Psychoacoustical abilities and Speech perception in noise in individuals with Sickle cell anemia.Journal of otology · 2025Article
- Sex differences in vocal learning ability in songbirds are linked with differences in flexible rhythm pattern perception.Animal behaviour · 2023Article
- Auditory Processing in Musicians, a Cross-Sectional Study, as a Basis for Auditory Training Optimization.Healthcare (Basel, Switzerland) · 2023Article
- Subconcussion revealed by sound processing in the brain.Exercise, sport & movement · 2023Article
- Athleticism and sex impact neural processing of sound.Scientific reports · 2022Article
- Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations.International journal of molecular sciences · 2022Article
- Behavioral and Immunohistochemical Evidence for Suppressive Effects of Goshajinkigan on Salicylate-Induced Tinnitus in Rats.Brain sciences · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
In humans, females process a sound's harmonics more robustly than males. As estrogen regulates auditory plasticity in a sex-specific manner in seasonally breeding animals, estrogen signaling is one hypothesized mechanism for this difference in humans. To investigate whether sex differences in harmonic encoding vary similarly across the reproductive cycle of mammals, we recorded frequency-following responses (FFRs) to a complex sound in male and female rats. Female FFRs were collected during both low and high levels of circulating estrogen during the estrous cycle. Overall, female rodents had larger harmonic encoding than male rodents, and greater harmonic strength was seen during periods of greater estrogen production in the females. These results argue that hormonal differences, specifically estrogen, underlie sex differences in harmonic encoding in rodents and suggest that a similar mechanism may underlie differences seen in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.