Evidence map›Paper›PMID 34819555›Full record

ArticleScientific reports2021

Usefulness of lung ultrasound for selecting asymptomatic older patients with COVID 19 pneumonia.

Chukwuma Okoye, Valeria Calsolaro, Alessandra Fabbri, Riccardo Franchi, Rachele Antognoli, Ludovica Zisca, Camilla Bianchi, Alessia Maria Calabrese, Sara Rogani, Fabio Monzani

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chukwuma OkoyeGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Valeria CalsolaroGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Alessandra FabbriGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Riccardo FranchiGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Rachele AntognoliGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Ludovica ZiscaLow Care Unit, Presidio Sanitario "Anna Torrigiani", Firenze, Italy.
Camilla BianchiLow Care Unit, Presidio Sanitario "Anna Torrigiani", Firenze, Italy.
Alessia Maria CalabreseGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Sara RoganiGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy.
Fabio MonzaniGeriatrics Unit, Department of Clinical & Experimental Medicine, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy. fabio.monzani@med.unipi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical and prognostic differences between symptomatic and asymptomatic older patients with COVID-19 are of great interest since frail patients often show atypical presentation of illness. Lung Ultrasound (LUS) has been proven to be a reliable tool for detecting early-phase COVID-19 pneumonic alterations. The current prospective bicentric study aimed to compare LUS score and 3-month overall mortality between asymptomatic and symptomatic older patients with COVID-19, according to frailty status. Patients were stratified according to LUS score tertiles and Clinical Frailty Scale categories. Survival rate was assessed by telephone interviews 3 months after discharge. 64 symptomatic (24 women, aged 80.0 ± 10.8 years) and 46 asymptomatic (31 women, aged 84.3 ± 8.8 years) were consecutively enrolled. LUS score resulted an independent predictor of 3-month mortality [OR 2.27 (CI95% 1.09-4.8), p = 0.03], and the highest mortality rate was observed in symptomatic and asymptomatic pre-frail and frail patients (70.6% and 66.7%, respectively) with greater LUS abnormalities (3rd tertile). In conclusion, LUS identified an acute interstitial lung involvement in most of the older asymptomatic patients. Mortality rate progressively increased according to clinical frailty and LUS score degree, resulting a reliable prognostic tool in both symptomatic and asymptomatic patients.

Indexed as

AgedAged, 80 and overAsymptomatic DiseasesCOVID-19FemaleHospitalizationHumansLungMalePneumoniaPrognosisProspective StudiesSARS-CoV-2Tomography, X-Ray ComputedUltrasonography

Identifiers

PMID34819555
PMCPMC8613196

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