Evidence map›Paper›PMID 34819551›Full record

ArticleScientific reports2021

Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus.

Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ebru DestanDepartment of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey.
Busra YukselDepartment of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey.
Bradley B TolarDepartment of Earth System Science, Stanford University, Stanford, CA, 94305, USA.
Esra AyanDepartment of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey.
Sam DeutschNutcracker Therapeutics, Inc 5858 Horton Street, Suite 540, Emeryville, CA, 94608, USA.
Yasuo YoshikuniThe US Department of Energy, Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Soichi WakatsukiDepartment of Structural Biology, Stanford University, Palo Alto, CA, 94305, USA. soichi.wakatsuki@stanford.edu.
Christopher A FrancisDepartment of Earth System Science, Stanford University, Stanford, CA, 94305, USA. caf@stanford.edu.
Hasan DeMirciDepartment of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey. hdemirci@stanford.edu.
Koç University · TRStanford University · USLawrence Berkeley National Laboratory · USPalo Alto University · USSLAC National Accelerator Laboratory · US

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
NIGMS NIH HHS P41 GM103393
6 · The paper itself

Abstract

The ammonia-oxidizing thaumarchaeal 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle is one of the most energy-efficient CO

Indexed as

Acyl Coenzyme AArchaeaArchaeal ProteinsCarbon DioxideCatalysisCrystallography, X-RayEnoyl-CoA HydrataseModels, MolecularProtein ConformationStructure-Activity RelationshipSubstrate Specificity3-hydroxybutyryl-coenzyme AAcyl Coenzyme AArchaeal ProteinsCarbon Dioxidecrotonyl-coenzyme AEnoyl-CoA Hydratase

Identifiers

PMID34819551
PMCPMC8613188
OpenAlexW3215949988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.