Evidence map›Paper›PMID 34819493›Full record

ArticleNature communications2021

Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mice.

Rémi Bos, Benoît Drouillas, Mouloud Bouhadfane, Emilie Pecchi, Virginie Trouplin, Sergiy M Korogod, Frédéric Brocard

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Body Temperature Regulation in the Rat by Muscle Tone.Acta physiologica (Oxford, England) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. TRPM3, TRPM4, and TRPM5 as thermo-sensitive channels.The journal of physiological sciences : JPS · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Rémi Bos *Institut de Neurosciences de la Timone (UMR7289), Aix-Marseille Université and CNRS, Marseille, France. remi.bos@univ-amu.fr.ORCID http://orcid.org/0000-0003-2639-3271
Benoît Drouillas *Institut de Neurosciences de la Timone (UMR7289), Aix-Marseille Université and CNRS, Marseille, France.
Mouloud BouhadfaneInstitut de Neurosciences de la Timone (UMR7289), Aix-Marseille Université and CNRS, Marseille, France.
Emilie PecchiInstitut de Neurosciences de la Timone (UMR7289), Aix-Marseille Université and CNRS, Marseille, France.
Virginie TrouplinInstitut de Neurosciences de la Timone (UMR7289), Aix-Marseille Université and CNRS, Marseille, France.
Sergiy M KorogodBogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine.ORCID http://orcid.org/0000-0002-8105-1904
Frédéric BrocardInstitut de Neurosciences de la Timone (UMR7289), Aix-Marseille Université and CNRS, Marseille, France. frederic.brocard@univ-amu.fr.ORCID http://orcid.org/0000-0001-9444-9586
Centre National de la Recherche Scientifique · FRNational Academy of Sciences of Ukraine · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bistable motoneurons of the spinal cord exhibit warmth-activated plateau potential driven by Na

Indexed as

Action PotentialsAnimalsAnimals, NewbornComputer SimulationDisease Models, AnimalFemaleGene SilencingHEK293 CellsHindlimbHumansLocomotionMaleMiceMotor NeuronsParesisPatch-Clamp TechniquesRecombinant ProteinsRyanodineSarcoplasmic Reticulum Calcium-Transporting ATPasesTrpm5 protein, mouseTRPM Cation Channels

Identifiers

PMID34819493
PMCPMC8613399
OpenAlexW3216515506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.