ArticleLight, science & applications2021
Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations.
Article in Light, science & applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 70 citations in OpenAlex.
- Label-free volumetric refractive-index imaging of fibrillar collagen architecture, assembly, and cell-associated remodeling.bioRxiv : the preprint server for biology · 2026Article
- High-speed, wide-field, fiber-based PS-OCT system with real-time surface Stokes feedback for circular input polarization.Biomedical optics express · 2026Article
- Label-free mid-infrared dichroism-sensitive photoacoustic microscopy for histostructural analysis of engineered heart tissues.Light, science & applications · 2026Article
- Fibre orientations in collagen-containing tissues revealed with computational scattered light imaging and polarimetric second harmonic generation microscopy.Scientific reports · 2025Article
- 3D printed anisotropic tissue simulants with embedded fluid capsules for medical simulation and training.Science advances · 2025Article
- Optical phenotyping using label-free microscopy and deep learning.Biophotonics discovery · 2025Article
- In situ expansion capacity evaluation of terminal alveoli in chronic obstructive pulmonary disease using an ultrathin optical coherence tomography catheter.Biomedical optics express · 2025Article
- Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations.Exploration (Beijing, China) · 2025Review
- Dichroism-sensitive photoacoustic imaging for in-depth estimation of the optic axis in fibrous tissue.Photoacoustics · 2025Article
- Three-dimensional fiber orientation mapping of ex vivo human brain at micrometer resolution.Npj imaging · 2025Article
- Absolute depth-resolved optic axis measurement with catheter-based polarization sensitive optical coherence tomography.Biomedical optics express · 2024Article
- TowardsFundamental research · 2024Review
- Inspiring a convergent engineering approach to measure and model the tissue microenvironment.Heliyon · 2024Review
- Optical Devices for the Diagnosis and Management of Spinal Cord Injuries: A Review.Biosensors · 2024Review
- Digital calibration method to enable depth-resolved all-fiber polarization sensitive optical coherence tomography with an arbitrary input polarization state.Biomedical optics express · 2024Article
- Skin characterization of diabetes mellitus revealed by polarization-sensitive optical coherence tomography imaging.Journal of biomedical optics · 2024Article
- Article
- Potential application of PS-OCT in the safety assessment of non-steroidal topical creams for atopic dermatitis treatment.Biomedical optics express · 2023Article
- Posterior scleral birefringence measured by triple-input polarization-sensitive imaging as a biomarker of myopia progression.Nature biomedical engineering · 2023Article
- The future of bioimage analysis: a dialog between mind and machine.Nature methods · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Collagen organization plays an important role in maintaining structural integrity and determining tissue function. Polarization-sensitive optical coherence tomography (PSOCT) is a promising noninvasive three-dimensional imaging tool for mapping collagen organization in vivo. While PSOCT systems with multiple polarization inputs have demonstrated the ability to visualize depth-resolved collagen organization, systems, which use a single input polarization state have not yet demonstrated sufficient reconstruction quality. Herein we describe a PSOCT based polarization state transmission model that reveals the depth-dependent polarization state evolution of light backscattered within a birefringent sample. Based on this model, we propose a polarization state tracing method that relies on a discrete differential geometric analysis of the evolution of the polarization state in depth along the Poincare sphere for depth-resolved birefringent imaging using only one single input polarization state. We demonstrate the ability of this method to visualize depth-resolved myocardial architecture in both healthy and infarcted rodent hearts (ex vivo) and collagen structures responsible for skin tension lines at various anatomical locations on the face of a healthy human volunteer (in vivo).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.