Evidence map›Paper›PMID 34819412›Full record

ArticleThe Journal of veterinary medical science2022

Suppurative meningoencephalitis and perineuritis caused by Streptococcus gallolyticus in a Japanese Black calf.

Mikuya Iwanaga, Naoto Imai, Ayaka Kamikawa, Kaho Shimada, Masatoshi Okura, Daisuke Takamatsu, Daijiro Ueda, Mizuki Nakayama, Tomoyuki Shibahara

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. The evolving story ofFrontiers in microbiology · 2026
    Review
  2. Experimental evaluation of pathogenicity and acquired immunity ofInternational journal for parasitology. Parasites and wildlife · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Mikuya IwanagaFukushima Prefectural Chuou Livestock Hygiene Service Center, 114-12 Arayashiki, Ganpouji, Tamakawa, Ishikawa, Fukushima 963-6311, Japan.
Naoto ImaiFukushima Prefectural Chuou Livestock Hygiene Service Center, 114-12 Arayashiki, Ganpouji, Tamakawa, Ishikawa, Fukushima 963-6311, Japan.
Ayaka KamikawaFukushima Prefectural Chuou Livestock Hygiene Service Center, 114-12 Arayashiki, Ganpouji, Tamakawa, Ishikawa, Fukushima 963-6311, Japan.
Kaho ShimadaChiba Prefectural Chuou Livestock Hygiene Service Office, 497 Iwatomimachi, Sakura, Chiba 285-0072, Japan.
Masatoshi OkuraDivision of Infectious Animal Disease Research, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
Daisuke TakamatsuDivision of Infectious Animal Disease Research, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
Daijiro UedaSaga Prefectural Livestock Hygiene Service Center, 2-7-4 Wakakusu, Saga, Saga 849-0928, Japan.
Mizuki NakayamaMiyazaki Prefectural Livestock Hygiene Service Center, 3151-1 Shimonaka, Sadowaracho, Miyazaki, Miyazaki 880-0212, Japan.
Tomoyuki ShibaharaDivision of Hygiene Management Research, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
National Livestock Breeding Center · JPMiyazaki Agricultural Research Institute · JPNational Agriculture and Food Research Organization · JPNational Institute of Animal Health · JPOsaka Prefecture University · JPSaga Prefectural Education Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 179-day-old calf, which was weak and stunted, showed neurological signs and was euthanized. Postmortem examination revealed extensive and severe cloudy area in the meninges, and pleural pneumonia. Gram-positive cocci were isolated from systemic organs. Biochemical and 16S rRNA gene sequence analyses identified the isolate as Streptococcus gallolyticus, and its subspecies was suggested to be gallolyticus (SGG). The isolate was classified as a novel sequence type (ST115) by the multilocus sequence typing scheme for SGG and showed susceptibility to penicillin, ampicillin, amoxicillin, florfenicol, sulfamethoxazole-trimethoprim, and chloramphenicol. Histopathologically, suppurative meningoencephalitis and perineuritis were detected. As SGG has been isolated solely from a cow with mastitis in Japan, this is the first SGG infection in a calf with suppurative meningoencephalitis and perineuritis in this country.

Indexed as

Cattle DiseasesMeningoencephalitisStreptococcal InfectionsAnimalsCattleFemaleMultilocus Sequence TypingRNA, Ribosomal, 16SStreptococcus gallolyticusRNA, Ribosomal, 16ScalfMultilocus sequence typingperineuritisStreptococcus gallolyticus subsp. gallolyticussuppurative meningoencephalitis

Identifiers

PMID34819412
PMCPMC8810337
OpenAlexW3217280537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.