Evidence map›Paper›PMID 34819397›Full record

ArticleMolecules and cells2021

Q-omics: Smart Software for Assisting Oncology and Cancer Research.

Jieun Lee, Youngju Kim, Seonghee Jin, Heeseung Yoo, Sumin Jeong, Euna Jeong, Sukjoon Yoon

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jieun LeeDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0002-4554-965X
Youngju KimDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0002-9176-1168
Seonghee JinDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0002-0434-6215
Heeseung YooDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0002-4814-0315
Sumin JeongDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0001-8193-8428
Euna JeongResearch Institute of Women's Health, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0002-8802-4140
Sukjoon YoonDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.ORCID https://orcid.org/0000-0001-7885-7117
Sookmyung Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid increase in collateral omics and phenotypic data has enabled data-driven studies for the fast discovery of cancer targets and biomarkers. Thus, it is necessary to develop convenient tools for general oncologists and cancer scientists to carry out customized data mining without computational expertise. For this purpose, we developed innovative software that enables user-driven analyses assisted by knowledge-based smart systems. Publicly available data on mutations, gene expression, patient survival, immune score, drug screening and RNAi screening were integrated from the TCGA, GDSC, CCLE, NCI, and DepMap databases. The optimal selection of samples and other filtering options were guided by the smart function of the software for data mining and visualization on Kaplan-Meier plots, box plots and scatter plots of publication quality. We implemented unique algorithms for both data mining and visualization, thus simplifying and accelerating user-driven discovery activities on large multiomics datasets. The present Q-omics software program (v0.95) is available at http://qomics.sookmyung.ac.kr.

Indexed as

Biomedical ResearchComputational BiologyGenomicsHumansNeoplasmsSoftwarebiomarkercancer bioinformaticsimmune infiltrateKaplan-Meier plotomics data miningsmart software

Identifiers

PMID34819397
PMCPMC8627836
OpenAlexW3214824459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.