Evidence map›Paper›PMID 34819323›Full record

ArticleBMJ open respiratory research2021

Home-based pulmonary rehabilitation early after hospitalisation in COPD (early HomeBase): protocol for a randomised controlled trial.

Narelle S Cox, Aroub Lahham, Christine F McDonald, Ajay Mahal, Paul O'Halloran, Graham Hepworth, Lissa Spencer, Renae J McNamara, Janet Bondarenko, Heather Macdonald and 20 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Narelle S CoxRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia Narelle.Cox@monash.edu.
Aroub LahhamRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Christine F McDonaldInstitute for Breathing and Sleep, Melbourne, Victoria, Australia.
Ajay MahalMelbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Paul O'HalloranSchool of Psychology and Public Health, La Trobe University, Melbourne, Victoria, Australia.
Graham HepworthStatistical Consulting Centre, University of Melbourne, Melbourne, Victoria, Australia.
Lissa SpencerRoyal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Renae J McNamaraPrince of Wales Hospital, Sydney, New South Wales, Australia.
Janet BondarenkoRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Heather MacdonaldWimmera Health Care Group, Horsham, Victoria, Australia.
Samantha GavinCoffs Harbour Health Campus, Coffs Harbour, New South Wales, Australia.
Angela T BurgeRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Caitlin Le MaitreAlfred Health, Melbourne, Victoria, Australia.
Cade RinginRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Elizabeth WebbRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Amanda NicholsRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Ling-Ling TsaiRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Nia LuxtonRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-2789-2275
Stephanie van HiltenRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Mary SantosPrince of Wales Hospital, Sydney, New South Wales, Australia.
Hayley CruteWimmera Health Care Group, Horsham, Victoria, Australia.
Megan ByrneWimmera Health Care Group, Horsham, Victoria, Australia.
Helen BoursinosRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Jennifer BroeRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Monique CorbettRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Tunya MarceauRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Brooke WarrickRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.
Claire BooteAlfred Health, Melbourne, Victoria, Australia.
Joanna MelinzCoffs Harbour Health Campus, Coffs Harbour, New South Wales, Australia.
Anne E HollandRespiratory Research@Alfred, Department of Immunology & Pathology, Monash University, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic obstructive pulmonary disease (COPD) is characterised by exacerbations of respiratory disease, frequently requiring hospital admission. Pulmonary rehabilitation can reduce the likelihood of future hospitalisation, but programme uptake is poor. This study aims to compare hospital readmission rates, clinical outcomes and costs between people with COPD who undertake a home-based programme of pulmonary rehabilitation commenced early (within 2 weeks) of hospital discharge with usual care.

methodsA multisite randomised controlled trial, powered for superiority, will be conducted in Australia. Eligible patients admitted to one of the participating sites for an exacerbation of COPD will be invited to participate. Participants will be randomised 1:1. Intervention group participants will undertake an 8-week programme of home-based pulmonary rehabilitation commencing within 2 weeks of hospital discharge. Control group participants will receive usual care and a weekly phone call for attention control. Outcomes will be measured by a blinded assessor at baseline, after the intervention (week 9-10 posthospital discharge), and at 12 months follow-up. The primary outcome is hospital readmission at 12 months follow-up. ETHICS AND DISSEMINATION: Human Research Ethics approval for all sites provided by Alfred Health (Project 51216). Findings will be published in peer-reviewed journals, conferences and lay publications. TRIAL REGISTRATION NUMBER: ACTRN12619001122145.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeEquivalence Trials as TopicExercise TherapyHospitalizationHumansPatient ReadmissionRandomized Controlled Trials as TopicCOPD exacerbationsexercisepulmonary rehabilitation

Identifiers

PMID34819323
PMCPMC8614151

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.