Evidence map›Paper›PMID 34819290›Full record

ArticleBMJ open2021

Seroprevalence of anti-SARS-CoV-2 antibodies in women attending antenatal care in eastern Ethiopia: a facility-based surveillance.

Nega Assefa, Lemma Demissie Regassa, Zelalem Teklemariam, Joseph Oundo, Lola Madrid, Yadeta Dessie, Jag Scott

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Seroprevalence of SARS-CoV-2 Antibodies in Africa: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Nega AssefaCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia negaassefa@yahoo.com.ORCID 0000-0003-0341-2329
Lemma Demissie RegassaCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.ORCID 0000-0002-5461-5348
Zelalem TeklemariamCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Joseph OundoLondon School of Hygiene & Tropical Medicine, London, UK.
Lola MadridLondon School of Hygiene & Tropical Medicine, London, UK.
Yadeta DessieCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Jag ScottLondon School of Hygiene & Tropical Medicine, London, UK.
Haramaya University · ETLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe conducted serosurveillance of anti-SARS-CoV-2 antibodies among pregnant women attending their first antenatal care.

settingThe surveillance was set in one referral hospital in Harar, one district hospital and one health centre located in Haramaya district in rural eastern Ethiopia.

participantsWe collected questionnaire data and a blood sample from 3312 pregnant women between 1 April 2020 and 31 March 2021. We selected 1447 blood samples at random and assayed these for anti-SARS-CoV-2 antibodies at Hararghe Health Research laboratory using WANTAI SARS-CoV-2 Rapid Test for total immunoglobulin. OUTCOME: We assayed for anti-SARS-CoV-2 antibodies and temporal trends in seroprevalence were analysed with a χ

resultsAmong 1447 sera tested, 83 were positive for anti-SARS-CoV-2 antibodies giving a crude seroprevalence of 5.7% (95% CI 4.6% to 7.0%). Of 160 samples tested in April-May 2020, none was seropositive; the first seropositive sample was identified in June and seroprevalence rose steadily thereafter (χ

conclusionsThis clinical convenience sample illustrates the dynamic of the SARS-CoV-2 epidemic in pregnant women in eastern Ethiopia; infection was rare before June 2020 but it spread in a linear fashion thereafter, rather than following intermittent waves, and reached 10% by the beginning of 2021. After 1 year of surveillance, most pregnant mothers remained susceptible.

Indexed as

COVID-19Prenatal CareAntibodies, ViralEthiopiaFemaleHospitals, DistrictHumansPregnancySARS-CoV-2Seroepidemiologic StudiesAntibodies, ViralCOVID-19health policyinfection controlprenatal diagnosisprotocols & guidelines

Identifiers

PMID34819290
PMCPMC8613670
OpenAlexW3215378206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.