ReviewBiomaterials research2021
Preparation of alginate hydrogel microparticles by gelation introducing cross-linkers using droplet-based microfluidics: a review of methods.
Review in Biomaterials research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Microstructure-driven modulation of polyphenol stability and antidiabetic activity in alginate microspheres loaded with pomegranate and tomato by-products.Journal of the science of food and agriculture · 2026Article
- Preparation of Targeted Delivery Materials and Their Application in Animal Production.Animals : an open access journal from MDPI · 2026Review
- Coordination-Driven Assembly of Alginate Networks: From Egg-Box Structures to Bioactive Delivery Applications.Gels (Basel, Switzerland) · 2026Review
- Assessment of water prophylaxis and biosafety in finfish aquaculture - current and emerging technologies.Frontiers in microbiology · 2026Review
- Biomimetic Nanogels Programmed for Irreversible-Electroporation-Primed Tumor Microenvironments to Elicit Durable Antitumor Immunity.Biomaterials research · 2026Article
- Effect of Sodium Alginate Concentration on the Physicochemical, Structural, Functional Attributes, and Consumer Acceptability of Gel Beads Encapsulating Tangerine Peel (Gels (Basel, Switzerland) · 2025Article
- Alginate Sphere-Based Soft Actuators.Gels (Basel, Switzerland) · 2025Review
- Emerging Trends in Microfluidic Biomaterials: From Functional Design to Applications.Journal of functional biomaterials · 2025Review
- Microbead Encapsulation Strategy for Efficient Production of Extracellular Vesicles Derived From Human Mesenchymal Stem Cells.Journal of extracellular vesicles · 2025Article
- In Vitro Release Dynamics of Atorvastatin-Loaded Alginate Particles for Enhanced Periodontal Treatment.Polymers · 2025Article
- Hydrogel Biocomposite of Alginate and Mucilage ofACS omega · 2025Article
- Histopathological and ultrastructural evaluations of giant African snail (Open veterinary journal · 2025Article
- A multifunctional injectable, self-healing, and adhesive hydrogel-based wound dressing stimulated diabetic wound healing with combined reactive oxygen species scavenging, hyperglycemia reducing, and bacteria-killing abilities.Journal of nanobiotechnology · 2024Article
- The Effects of Endometrial Mesenchymal Stem Cells on TheInternational journal of fertility & sterility · 2024Article
- Enhancing Bone Cement Efficacy with Hydrogel Beads Synthesized by Droplet Microfluidics.Nanomaterials (Basel, Switzerland) · 2024Article
- The use of droplet-based microfluidic technologies for accelerated selection ofBiology methods & protocols · 2024Review
- scMAR-Seq: a novel workflow for targeted single-cell genomics of microorganisms using radioactive labeling.mSystems · 2023Article
- Enhancing Soil Resilience: Bacterial Alginate Hydrogel vs. Algal Alginate in Mitigating Agricultural Challenges.Gels (Basel, Switzerland) · 2023Article
- Recent Progress of Droplet Microfluidic Emulsification Based Synthesis of Functional Microparticles.Global challenges (Hoboken, NJ) · 2023Review
- Bone/cartilage organoid on-chip: Construction strategy and application.Bioactive materials · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This review examines the preparation of alginate hydrogel microparticles by using droplet-based microfluidics, a technique widely employed for its ease of use and excellent control of physicochemical properties, with narrow size distribution. The gelation of alginate is realized "on-chip" and/or "off-chip", depending on where cross-linkers are introduced. Various strategies are described and compared. Microparticle properties such as size, shape, concentration, stability and mechanical properties are discussed. Finally, we consider future perspectives for the preparation of hydrogel microparticles and their potential applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.