Evidence map›Paper›PMID 34819117›Full record

ArticleTrials2021

Using a WeChat mini-program-based lactation consultant intervention to increase the consumption of mother's own milk by preterm infants in the neonatal intensive care unit: a study protocol for a cluster randomized controlled trial.

Jie Huo, Xinping Wu, Chuanli Gu, Zhangbin Yu, Jun Zhang, Xiaohui Chen, Jingai Zhu, Feng Liu, Beibei Liu, Qianqian Li and 1 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04383379 (Evidence-Based Practice for Improving Quality), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04383379 naunknown statusnot on this map

Evidence-Based Practice for Improving Quality(EPIQ) to Improve the Rate of Mother's Own Milk Feeding of Premature Infants in NICU: Study Protocol for a Cluster Randomized Controlled Trial

TypeinterventionalSponsorNanjing Medical UniversityRan2020 to 2022Enrolled1,500ConditionsQuality Improvement, Breast-feeding, Premature InfantArmsExperimental: Intervention group
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Alberta family integrated careFrontiers in pediatrics · 2026
    Review
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jie Huo *Department of Neonatology, Yangzhou Maternity and Child Health Care Hospital, Yangzhou, 225002, China.
Xinping Wu *Department of Neonatology, Yangzhou Maternity and Child Health Care Hospital, Yangzhou, 225002, China.
Chuanli GuDepartment of Neonatology, Yangzhou Maternity and Child Health Care Hospital, Yangzhou, 225002, China.
Zhangbin YuDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China.
Jun ZhangDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China.
Xiaohui ChenDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China.
Jingai ZhuDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China.
Feng LiuDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China.
Beibei LiuDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China.
Qianqian LiDepartment of Neonatology, Xuzhou Maternity and Child Health Care Hospital, Xuzhou, 221009, China.
Shuping HanDepartment of Neonatology, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University, Nanjing, 210004, China. shupinghan@njmu.edu.cn.ORCID http://orcid.org/0000-0003-2077-1673
Nanjing Maternity and Child Health Care Hospital · CNHangzhou Women’s Hospital · CNMaternal and Child Health Hospital of Xuzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe benefits of mother's own milk (MOM) for preterm infants have been widely recognized. Many studies have shown that the rate of breastfeeding of premature infants remains very low. Although many studies use measures to promote breastfeeding, few high-quality cluster randomized controlled studies have evaluated the effectiveness of these measures. WeChat is an instant messaging software for smart terminals, and WeChat mini-programs have been widely used to promote health and self-management in China. Based on this background, we designed a randomized controlled study based on WeChat mini-programs to promote MOM feeding of premature infants in the neonatal intensive care unit (NICU). METHODS/

designThis study will evaluate the effectiveness of WeChat mini-programs to increase the consumption of MOM feeding in twelve NICUs in Jiangsu Province, namely, six "intervention" NICUs and six "control" NICUs. The study process is as follows: (1) design and preparation, (2) NICU recruitment and training, (3) interpretation and analysis of baseline data, (4) quality control implementation process, and (5) data analysis feedback and publication of study reports. The primary outcome is the proportion of MOM feeding of premature infants during NICU hospitalization. The secondary outcomes are as follows: (1) time to initiation of MOM feeding (hours) and proportion of first-time MOM feeding (%), (2) duration of parenteral nutrition (days), (3) time to total gastrointestinal feeding (days), (4) hospitalization time and hospitalization cost, and (5) incidence of complications (necrotizing enterocolitis, bronchopulmonary dysplasia, feeding intolerance, late-onset sepsis, retinopathy of prematurity). DISCUSSION: This study is the first cluster randomized controlled trial on the intervention of using a WeChat mini-program-based lactation consultant for premature infants in the NICU in China. We hope this study can improve the consumption of MOM by NICU premature infants during hospitalization through the intervention of WeChat mini-programs.

trial registrationClinicalTrials.gov NCT04383379. Registered on May 5, 2020.

Indexed as

ConsultantsIntensive Care Units, NeonatalBreast FeedingFemaleHealth PromotionHumansInfantInfant, NewbornInfant, PrematureLactationMilk, HumanMothersRandomized Controlled Trials as TopicLactation consultantMother’s own milk feedingPremature infantRandomized controlled trialWeChat mini-programs

Identifiers

PMID34819117
PMCPMC8611400
OpenAlexW3137490223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.