Evidence map›Paper›PMID 34819115›Full record

Trial reportTrials2021

Supplement study update for Reach Out: a multi-arm randomized trial of behavioral interventions for hypertension initiated in the emergency department: Reach Out Cognition.

Lesli E Skolarus, Mackenzie Dinh, Kelley M Kidwell, Zahera Farhan, Candace Whitfield, Deborah A Levine, William J Meurer

Registry-linked trialAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03422718 (Reach Out), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03422718 nacompletednot on this map

Reach Out: Randomized Clinical Trial of Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems

TypeinterventionalSponsorUniversity of MichiganRan2019 to 2021Enrolled488ConditionsHypertensionArmsHealthy Behavior Texts, No healthy behavior texts, BP Monitoring Daily Via Text Messaging, BP Monitoring Weekly Via Text Messaging, Physician appointment and transportation scheduling
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lesli E SkolarusDepartment of Neurology, University of Michigan, Ann Arbor, USA.
Mackenzie DinhDepartment of Emergency Medicine, University of Michigan, Ann Arbor, USA. mdome@umich.edu.ORCID http://orcid.org/0000-0003-1618-8012
Kelley M KidwellDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, USA.
Zahera FarhanDepartment of Emergency Medicine, University of Michigan, Ann Arbor, USA.
Candace WhitfieldDepartment of Emergency Medicine, University of Michigan, Ann Arbor, USA.
Deborah A LevineDepartment of Neurology, University of Michigan, Ann Arbor, USA.
William J MeurerDepartment of Neurology, University of Michigan, Ann Arbor, USA.

Funding

Reach Out: Randomized Clinical Trial of Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health SystemsR01MD011516 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MEURER, WILLIAM JOSEPH, SKOLARUS, LESLI ELIZABETH · 2017 to 2020
$3.3M
NIMHD NIH HHS R01 MD011516NIMHD NIH HHS R01MD011516-04S1
6 · The paper itself

Abstract

backgroundReach Out is a factorial trial studying multicomponent behavioral interventions to reduce blood pressure in hypertensive emergency department patients. The original study protocol was published in June 2020. Here, we describe the updated protocol, including a supplemental study, Reach Out Cognition. Reach Out Cognition is a remote study that will assess the acceptability, feasibility, and satisfaction of digital, self-administered cognitive assessments and Bluetooth-enabled, self-measured blood pressure monitoring in the Reach Out population. We will also estimate the prevalence of mild cognitive impairment in Reach Out participants.

methodsReach Out Cognition includes remote enrollment and follow-up assessments. Reach Out Cognition extends Reach Out data collection past the current 12 months to 15 and 18 months. Participants will be Reach Out participants who complete their 12-month outcome assessments and opt to continue in the cohort study. Participants will continue to receive the Reach Out intervention, consisting of (1) daily healthy behavior text messaging and (2) weekly self-measured blood pressure monitoring. Blood pressure will be measured using Bluetooth-enabled self-measured blood pressure monitoring devices, and cognition will be measured using digital self-administered cognitive assessments at 12, 15, and 18 months. DISCUSSION: Reach Out Cognition will explore the potential of remote, digital, self-administered assessments of blood pressure and cognition among predominantly working-age Black Americans. Reach Out Cognition will inform future clinical trials and clinical remote monitoring of blood pressure and cognition that may lead to new approaches to treating and reducing hypertension and cognitive disparities.

trial registrationClinicalTrials.gov NCT03422718. The record was first available to the public on January 30, 2018, prior to the enrollment of patients on March 25, 2019.

Indexed as

HypertensionText MessagingCognitionCohort StudiesEmergency Service, HospitalHumansCognitionEmergency MedicineHealth EquityHypertensionMultiphase Optimization Strategy

Identifiers

PMID34819115
PMCPMC8611628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.