Evidence map›Paper›PMID 34819108›Full record

ArticleBiomedical engineering online2021

Characterization and in vitro assessment of three-dimensional extrusion Mg-Sr codoped SiO

Chengyong Li, Tingting Yan, Zhenkai Lou, Zhimin Jiang, Zhi Shi, Qinghua Chen, Zhiqiang Gong, Bing Wang

Open access · goldAbstract read
In one paragraph

Article in Biomedical engineering online, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Magnetic FeAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chengyong LiDepartment of Orthopedics, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, 650032, China.
Tingting YanFaculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, China.
Zhenkai LouDepartment of Orthopedics, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, 650032, China.
Zhimin JiangFaculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, China.
Zhi ShiDepartment of Orthopedics, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, 650032, China.
Qinghua ChenFaculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, China.
Zhiqiang GongDepartment of Orthopedics, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, 650032, China.
Bing WangDepartment of Orthopedics, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, 650032, China. drbingwang@163.com.
Kunming Medical University · CNKunming University of Science and Technology · CNFirst Affiliated Hospital of Kunming Medical University · CN

Funding

Fondo para la Investigación Científica y Tecnológica CXTD201805National Natural Science Foundation of China 81760029National Natural Science Foundation of China 82060416Yunnan Province Clinical Center for Bone and joint Diseases ZX2019-03-04
6 · The paper itself

Abstract

backgroundLarge bone defects have always been a great challenge for orthopedic surgeons. The use of a good bone substitute obtained by bone tissue engineering (BTE) may be an effective treatment method. Artificial hydroxyapatite, a commonly used bone defect filler, is the main inorganic component of bones. Because of its high brittleness, fragility, and lack of osteogenic active elements, its application is limited. Therefore, its fragility should be reduced, its osteogenic activity should be improved, and a more suitable scaffold should be constructed.

methodsIn this study, a microhydroxyapatite whisker (mHAw) was developed, which was doped with the essential trace active elements Mg

resultsFour types of scaffolds were obtained: mHAw-SiO

conclusionsThese composite porous scaffolds not only have acceptable physical and chemical properties suitable for BTE but also have higher osteogenic bioactivity and can possibly serve as potential bone repair materials.

Indexed as

OsteogenesisTissue ScaffoldsAnimalsBiomedical EngineeringCell DifferentiationPorosityRatsRats, Sprague-DawleySilicon DioxideTissue EngineeringVibrissaeSilicon DioxideBone tissue engineeringExtrusion moldingMicron hydroxyapatite whiskersPorous ceramic scaffold

Identifiers

PMID34819108
PMCPMC8611959
OpenAlexW3170110444

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.