Evidence map›Paper›PMID 34819096›Full record

ArticleHealth and quality of life outcomes2021

Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study.

Lucas Molinari Veloso da Silveira, Adriana Silveira Almeida, Felipe C Fuchs, Aline Gonçalves Silva, Marcelo Balbinot Lucca, Samuel Scopel, Sandra C Fuchs, Flávio D Fuchs

Abstract read
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Characterizing heterogeneity in health-related quality of life trajectories in coronary artery disease: a longitudinal latent Markov analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucas Molinari Veloso da SilveiraPostgraduate Studies Program in Cardiology, School of Medicine, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Porto Alegre, Brazil.
Adriana Silveira AlmeidaPostgraduate Studies Program in Cardiology, School of Medicine, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Porto Alegre, Brazil.
Felipe C FuchsPostgraduate Studies Program in Cardiology, School of Medicine, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Porto Alegre, Brazil.
Aline Gonçalves SilvaHospital de Clínicas de Porto Alegre, INCT PREVER, CPC, 5º. and., Ramiro Barcelos, Porto Alegre, RS, 2350, 90035-903, Brazil.
Marcelo Balbinot LuccaPostgraduate Studies Program in Cardiology, School of Medicine, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Porto Alegre, Brazil.
Samuel ScopelHospital de Clínicas de Porto Alegre, INCT PREVER, CPC, 5º. and., Ramiro Barcelos, Porto Alegre, RS, 2350, 90035-903, Brazil.
Sandra C FuchsPostgraduate Studies Program in Cardiology, School of Medicine, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Porto Alegre, Brazil. sfuchs@hcpa.edu.br.ORCID http://orcid.org/0000-0001-6351-9588
Flávio D FuchsPostgraduate Studies Program in Cardiology, School of Medicine, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), RS, Porto Alegre, Brazil.

Funding

Hospital de Clínicas de Porto Alegre 13-0171National Council for Scientific and Technological Development (CNPq) 302966/2019-6National Council for Scientific and Technological Development (CNPq) 309023/2015-7Programa de Excelência Acadêmica (PROEX), da CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) 0566/2019
6 · The paper itself

Abstract

backgroundClinical, surgical, and percutaneous strategies similarly prevent major cardiovascular events in patients with stable coronary artery disease (CAD). The possibility that these strategies have differential effects on health-related quality of life (HRQoL) has been debated, particularly in patients treated outside clinical trials.

methodsWe assigned 454 patients diagnosed with CAD during an elective diagnostic coronary angiography to coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or optimal medical treatment (OMT), and followed them for an average of 5.2 ± 1.5 years. HRQoL was assessed using a validated Brazilian version of the 12-Item Short-Form Health Survey questionnaire. The association between therapeutic strategies and quality of life scores was tested using variance analysis and adjusted for confounders in a general linear model.

resultsThere were no differences in the mental component summary scores in the follow-up evaluation by therapeutic strategies: 51.4, 53.7, and 52.3 for OMT, PCI, and CABG, respectively. Physical component summary scores were higher in the PCI group than the CABG and OMT groups (46.4 vs. 42.9 and 43.8, respectively); however, these differences were no longer different after adjustment for confounding variables.

conclusionIn a long-term follow-up of patients with stable CAD, HRQoL did not differ in patients treated by medical, percutaneous, or surgical treatments.

Indexed as

Coronary Artery DiseasePercutaneous Coronary InterventionCohort StudiesHumansQuality of LifeTreatment OutcomeCardiac surgeryCohort studyPercutaneous coronary interventionQuality of lifeStable coronary artery disease

Identifiers

PMID34819096
PMCPMC8611891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.