Evidence map›Paper›PMID 34819070›Full record

Trial reportHarm reduction journal2021

The impact of COVID-19 on people who inject drugs in New York City: increased risk and decreased access to services.

Yesenia Aponte-Melendez, Pedro Mateu-Gelabert, Chunki Fong, Benjamin Eckhardt, Shashi Kapadia, Kristen Marks

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Harm reduction journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03214679 (Accessible Care Intervention for Engaging People Who Inject Illicit Drugs in HCV Care), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03214679 nacompletednot on this map

Accessible Care Intervention for Engaging People Who Inject Illicit Drugs in HCV Care

TypeinterventionalSponsorCity University of New York, School of Public HealthRan2017 to 2021Enrolled167ConditionsHepatitis C, People Who Inject Drugs, PWID, HCV CoinfectionArmsAccessible Care, Usual Care
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yesenia Aponte-MelendezCUNY Graduate School of Public Health and Health Policy, Institute for Implementation Science in Population Health (ISPH), 55 West 125th Street, New York, NY, 10027, USA. Yesenia.Aponte-Melendez@sph.cuny.edu.ORCID 0000-0003-1288-7684
Pedro Mateu-GelabertCUNY Graduate School of Public Health and Health Policy, Institute for Implementation Science in Population Health (ISPH), 55 West 125th Street, New York, NY, 10027, USA.
Chunki FongCUNY Graduate School of Public Health and Health Policy, Institute for Implementation Science in Population Health (ISPH), 55 West 125th Street, New York, NY, 10027, USA.
Benjamin EckhardtNYU School of Medicine, 550 First Avenue, New York, NY, 10016, USA.
Shashi KapadiaWeill Cornell Medicine, 1305 York Ave 4th Floor, New York, NY, 10021, USA.
Kristen MarksWeill Cornell Medicine, 1305 York Ave 4th Floor, New York, NY, 10021, USA.

Funding

BEHAVIORAL SCI TRAINING IN DRUG ABUSE RESEARCHT32DA007233 · NIDA · PUBLIC HEALTH SOLUTIONS · PI GOLDSAMT, LLOYD A · 1985 to 2023
$20.2M
Accessible Care Intervention for Engaging People who Inject Illicit Drugs (PWID) in Hepatitis C CareR01DA041298 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI MARKS, KRISTEN M, MATEU-GELABERT, PEDRO · 2016 to 2020
$2.8M
Integrated Care for Hepatitis C: Current Uptake & Impact on Future TreatmentK01DA048172 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI KAPADIA, SHASHI · 2019 to 2023
$948k
NIDA NIH HHS K01 DA048172NIDA NIH HHS K01DA048172NIDA NIH HHS R01 DA041298NIDA NIH HHS R01DA041298NIDA NIH HHS T32 DA007233
6 · The paper itself

Abstract

backgroundWhile people who inject drugs (PWID) are vulnerable to the adverse outcomes of events like COVID-19, little is known regarding the impact of the current pandemic on PWID. We examine how COVID-19 has affected PWID in New York City across four domains: substance use, risk behaviors, mental health, and service utilization.

methodsAs part of a randomized trial to improve access to HCV treatment for PWID, we recruited 165 participants. Eligibility criteria included detectable HCV RNA and recent drug injection. The present cross-sectional analysis is based on a subsample of 106 participants. We compared responses between two separate samples: 60 participants interviewed prior to the pandemic (pre-COVID-19 sample) and 46 participants interviewed during the pandemic (COVID-19 sample). We also assessed differences by study group [accessible care (AC) and usual care (UC)].

resultsCompared to the pre-COVID-19 sample, those interviewed during COVID-19 reported higher levels of mental health issues, syringe reuse, and alcohol consumption and greater reductions in syringe-service programs and buprenorphine utilization. In the analysis conducted by study group, the UC group reported significantly higher injection risk behaviors and lower access to buprenorphine treatment during COVID-19, while during the same period, the AC group reported lower levels of substance use and injection risk behaviors.

conclusionThe current study provides insight on how COVID-19 has negatively affected PWID. Placing dispensing machines of harm-reduction supplies in communities where PWID live and increasing secondary exchange, mobile services, and mail delivery of supplies may help maintain access to lifesaving supplies during big events, such as COVID-19. Trial registration ClinicalTrials.gov NCT03214679. Registered July 11 2017. https://clinicaltrials.gov/ct2/show/NCT03214679 .

Indexed as

COVID-19HIV InfectionsPharmaceutical PreparationsSubstance Abuse, IntravenousCross-Sectional StudiesHumansNew York CitySARS-CoV-2Pharmaceutical PreparationsBig eventsCOVID-19HCVNew York CityPeople who inject drugs

Identifiers

PMID34819070
PMCPMC8611635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.