Evidence map›Paper›PMID 34819025›Full record

ArticleBMC public health2021

Funding patterns for biomedical research and infectious diseases burden in Gabon.

Olouyomi Scherif Adegnika, Yabo Josiane Honkpehedji, Fabrice Mougeni Lotola, Selidji Todagbe Agnandji, Ayola Akim Adegnika, Bertrand Lell, Elisa Sicuri

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 6 countries.

Olouyomi Scherif AdegnikaCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon. scherif.adegnika@cermel.org.
Yabo Josiane HonkpehedjiCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Fabrice Mougeni LotolaCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Selidji Todagbe AgnandjiCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Ayola Akim AdegnikaCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Bertrand LellCentre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
Elisa SicuriISGlobal, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain.
Centre de Recherche Médicales de Lambaréné · GALeiden University Medical Center · NLMedical University of Vienna · ATUniversitat de Barcelona · ESUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiomedical research plays an important role in improving health. There seems to exist a negative correlation between the amount of biomedical research funding and disease burden from all Sub-Saharan African countries. In this study, we describe funding patterns for biomedical research, explore the correlation between funding and burden of diseases, and quantify inequalities in funds distribution across diseases in Gabon over the period 2005-2015.

methodsData on medical research funds from 2005 to 2015 were retrieved through a structured questionnaire distributed to Gabonese biomedical research institutions and by consulting online databases. Data on the burden of diseases were gathered from the World Health Organization and the Institute for Health Metrics and Evaluation. We used Kendall rank correlation coefficient to explore the correlation between cumulative funds over time and the burden of disease. The inequality distribution of funding across diseases was assessed through Gini coefficient and Lorenz curve.

resultsBiomedical research funding was characterized by a remarkable growth from 2005 to 2010 and a decline from 2010 to 2014. Funds were mostly from external sources and from partnerships. There was inequality in research funds allocation across diseases and malaria was far the most funded disease. There was a significant negative correlation between cumulative funding and the burden of HIV, tuberculosis, and of Helminthiasis (from 2006 to 2010) suggesting that research may be contributing to the management of such diseases. A positive, although not significant, correlation was found between cumulative funds and malaria burden.

conclusionsThe negative correlation between HIV and tuberculosis cumulative funding and burden suggests that research may be contributing to the management of such diseases but further research is needed to assess the causal direction of such as relationship. As the burden of non-communicable diseases is increasing, more research funds should be focused on those. While research partnerships have been and will remain fundamental, Gabon should increase the amount of national funds to overcome periods of reduced research funding flows from abroad.

Indexed as

Biomedical ResearchCommunicable DiseasesFinancial ManagementCost of IllnessGabonHumansGabonInfectious diseasesResearch financingResearch partnership

Identifiers

PMID34819025
PMCPMC8611934
OpenAlexW3216983671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.