Evidence map›Paper›PMID 34818767›Full record

ReviewThe Science of the total environment2022

Mucormycosis (black fungus) ensuing COVID-19 and comorbidity meets - Magnifying global pandemic grieve and catastrophe begins.

Karthika Pushparaj, Haripriya Kuchi Bhotla, Vijaya Anand Arumugam, Manikantan Pappusamy, Murugesh Easwaran, Wen-Chao Liu, Utthapon Issara, Kannan R R Rengasamy, Arun Meyyazhagan, Balamuralikrishnan Balasubramanian

Open access · bronzeAbstract readReview
In one paragraph

Review in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Mucormycosis: A Rare disease to Notifiable Disease.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  4. The Review of Ophthalmic Symptoms in COVID-19.Clinical ophthalmology (Auckland, N.Z.) · 2024
    Review
  5. Hyphae ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Karthika PushparajDepartment of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore 641 043, Tamil Nadu, India.
Haripriya Kuchi BhotlaDepartment of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India.
Vijaya Anand ArumugamDepartment of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Manikantan PappusamyDepartment of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India.
Murugesh EaswaranInternational Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India.
Wen-Chao LiuDepartment of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, PR China.
Utthapon IssaraDivision of Food Science and Technology Management, Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi, Pathum Thani 12110, Thailand.
Kannan R R RengasamyGreen Biotechnologies Research Centre of Excellence, University of Limpopo, Private Bag X1106, Polokwane, Sovenga 0727, South Africa.
Arun MeyyazhaganDepartment of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India. Electronic address: arun47biotech@gmail.com.
Balamuralikrishnan BalasubramanianDepartment of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, South Korea. Electronic address: bala.m.k@sejong.ac.kr.
Christ University · INAvinashilingam University · INBharathiar University · INGuangdong Ocean University · CNInternational Centre for Genetic Engineering and Biotechnology · INRajamangala University of Technology · THSejong University · KRUniversity of Limpopo · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post COVID-19, mucormycosis occurred after the SARS-CoV-2 has rampaged the human population and is a scorching problem among the pandemic globally, particularly among Asian countries. Invasive mucormycosis has been extensively reported from mild to severe COVID-19 survivors. The robust predisposing factor seems to be uncontrolled diabetes mellitus, comorbidity and immunosuppression acquired through steroid therapy. The prime susceptive reason for the increase of mucormycosis cases is elevated iron levels in the serum of the COVID survivors. A panoramic understanding of the infection has been elucidated based on clinical manifestation, genetic and non- genetic mechanisms of steroid drug administration, biochemical pathways and immune modulated receptor associations. This review lime-lights and addresses the "What", "Why", "How" and "When" about the COVID-19 associated mucormycosis (CAM) in a comprehensive manner with a pure intention to bring about awareness to the common public as the cases are inevitably and exponentially increasing in India and global countries as well. The article also unearthed the pathogenesis of mucormycosis and its association with the COVID-19 sequela, the plausible routes of entry, diagnosis and counter remedies to keep the infection at bay. Cohorts of case reports were analysed to spotlight the link between the pandemic COVID-19 and the nightmare-mucormycosis.

Indexed as

COVID-19MucormycosisComorbidityFungiHumansPandemicsSARS-CoV-2ComorbidityCOVID-19 induced MucormycosisDexamethasoneDiagnosisHyperglycemiaKetosisSecondary infections

Identifiers

PMID34818767
PMCPMC8443313
OpenAlexW3200268383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.