Evidence map›Paper›PMID 34818706›Full record

ArticleArchives of plastic surgery2021

Volumetric change of the latissimus dorsi muscle after postoperative chemotherapy and radiotherapy in immediate breast reconstruction with an extended latissimus dorsi musculocutaneous flap: final results from serial studies.

Kyeong Ho Song, Won Seok Oh, Jae Woo Lee, Min Wook Kim, Dae Kyun Jeong, Seong Hwan Bae, Hyun Yul Kim, Youn Joo Jung, Ki Seok Choo, Kyung Jin Nam and 3 more

Open access · goldAbstract read
In one paragraph

Article in Archives of plastic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kyeong Ho SongFour Seasons Plastic Surgery Clinic, Busan, Korea.
Won Seok OhDepartment of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Yangsan, Korea.
Jae Woo LeeDepartment of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Yangsan, Korea.
Min Wook KimDepartment of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Yangsan, Korea.
Dae Kyun JeongDepartment of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Yangsan, Korea.
Seong Hwan BaeDepartment of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Yangsan, Korea.
Hyun Yul KimDepartment of Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea.
Youn Joo JungDepartment of Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea.
Ki Seok ChooDepartment of Radiology, Pusan National University School of Medicine, Yangsan, Korea.
Kyung Jin NamDepartment of Radiology, Pusan National University School of Medicine, Yangsan, Korea.
Ji Hyeon JooDepartment of Radiation Oncology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.
Mi Sook YunDivision of Biostatistics, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.
Su Bong NamDepartment of Plastic and Reconstructive Surgery, Pusan National University School of Medicine, Yangsan, Korea.
Pusan National University · KRPusan National University Yangsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast reconstruction using an extended latissimus dorsi (eLD) flap can supplement more volume than reconstruction using various local flaps after partial mastectomy, and it is a valuable surgical method since the reconstruction area is not limited. However, when performing reconstruction, the surgeon should consider latissimus dorsi (LD) volume reduction due to postoperative chemotherapy (POCTx) and postoperative radiotherapy (PORTx). To evaluate the effect of POCTx and PORTx on LD volume reduction, the effects of each therapy-both separately and jointly-need to be demonstrated. The present study quantified LD volume reduction in patients who underwent POCTx and PORTx after receiving breast-conserving surgery (BCS) with an eLD flap.

methodsThis study included 48 patients who received immediate breast reconstruction using an eLD flap from January 2013 to March 2017, had chest computed tomography (CT) 7-10 days after surgery and 10-14 months after radiotherapy completion, and were observed for more than 3 years postoperatively. One surgeon performed the breast reconstruction procedures, and measurements of breast volume were obtained from axial CT views, using a picture archiving and communication system. A P-value <0.05 was the threshold for statistical significance.

resultsThe average volume reduction of LD at 10-14 months after completing POCTx and PORTx was 64.5% (range, 42.8%-81.4%) in comparison to the volume measured 7-10 days after surgery. This change was statistically significant (P<0.05).

conclusionsBased on the findings of this study, when harvesting an eLD flap, surgeons should anticipate an average LD volume reduction of 64.5% if chemotherapy and radiotherapy are scheduled after BCS with an eLD flap.

Indexed as

Breast reconstructionChemotherapyMammaplastyRadiotherapy

Identifiers

PMID34818706
PMCPMC8627943
OpenAlexW3217787095

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.