Evidence map›Paper›PMID 34818601›Full record

ReviewEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2022

The impact of the prolonged COVID-19 pandemic on stress resilience and mental health: A critical review across waves.

Mirko Manchia, Anouk W Gathier, Hale Yapici-Eser, Mathias V Schmidt, Dominique de Quervain, Therese van Amelsvoort, Jonathan I Bisson, John F Cryan, Oliver D Howes, Luisa Pinto and 4 more

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 225 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
225citing papers in PubMed, 6 pooled it
50.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

225 citing papers in PubMed, 6 syntheses or guidelines pooled it, 470 citations in OpenAlex.

  1. Pooled it
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  4. The Influence of the COVID-19 Pandemic on Social Anxiety: A Systematic Review.International journal of environmental research and public health · 2023
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  20. Educating during the COVID-19 Pandemic: An Educator Perspective on Mental Health.Disaster medicine and public health preparedness · 2026
    Article

165 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 10 countries.

Mirko ManchiaSection of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy; Department of Pharmacology, Dalhousie University, Halifax, NS, Abbreviation.
Anouk W GathierDepartment of Psychiatry (GGZ inGeest), Amsterdam UMC (location VUmc), Vrije University, Amsterdam Public Health and Amsterdam Neuroscience research institutes, Amsterdam, Netherlands.
Hale Yapici-EserDepartment of Psychiatry, Koç University School of Medicine, Istanbul, Turkey; Research Center for Translational Medicine, Koç University, Istanbul, Turkey.
Mathias V SchmidtResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich, Germany.
Dominique de QuervainDivision of Cognitive Neuroscience, Department of Psychology, Department of Medicine, University of Basel, Switzerland.
Therese van AmelsvoortDepartment of Psychiatry and Neuropsychology, Maastricht University, Maastricht, Netherlands.
Jonathan I BissonDivision of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, United Kingdom.
John F CryanDept Anatomy & Neuroscience, University College Cork, Cork, Ireland & APC Microbiome Ireland, University College Cork, Cork, Ireland.
Oliver D HowesKing's College London, London, SE5 8AF Imperial College London, London, W12 0NN Lundbeck A/v, Valby, Denmark.
Luisa PintoLife and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Nic J van der WeeDepartment of Psychiatry, Leiden University Medical Center, LUMC Neuroscience and Leiden Institute for Brain and Cognition, Leiden, Netherlands.
Katharina DomschkeDepartment of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Basics in NeuroModulation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Igor BranchiCenter for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy.
Christiaan H VinkersDepartment of Psychiatry (GGZ inGeest), Amsterdam UMC (location VUmc), Vrije University, Amsterdam Public Health and Amsterdam Neuroscience research institutes, Amsterdam, Netherlands; Department of Anatomy and Neurosciences, Amsterdam UMC (location VUmc), Vrije University, Amsterdam, Netherlands. Electronic address: c.vinkers@amsterdamumc.nl.
Amsterdam Neuroscience · NLCardiff University · GBDalhousie University · CAIstituto Superiore di Sanità · ITKoç University · TRLeiden University Medical Center · NLLundbeck (Denmark) · DKMaastricht University · NLMax Planck Institute of Psychiatry · DEUniversity College Cork · IEUniversity of Basel · CHUniversity of Freiburg · DEUniversity of Minho · PT

Funding

Medical Research Council MC_U120097115Medical Research Council MR/N027078/1
6 · The paper itself

Abstract

The global public health crisis caused by COVID-19 has lasted longer than many of us would have hoped and expected. With its high uncertainty and limited control, the COVID-19 pandemic has undoubtedly asked a lot from all of us. One important central question is: how resilient have we proved in face of the unprecedented and prolonged coronavirus pandemic? There is a vast and rapidly growing literature that has examined the impact of the pandemic on mental health both on the shorter (2020) and longer (2021) term. This not only concerns pandemic-related effects on resilience in the general population, but also how the pandemic has challenged stress resilience and mental health outcomes across more specific vulnerable population groups: patients with a psychiatric disorder, COVID-19 diagnosed patients, health care workers, children and adolescents, pregnant women, and elderly people. It is challenging to keep up to date with, and interpret, this rapidly increasing scientific literature. In this review, we provide a critical overview on how the COVID-19 pandemic has impacted mental health and how human stress resilience has been shaped by the pandemic on the shorter and longer term. The vast literature is dominated by a wealth of data which are, however, not always of the highest quality and heavily depend on online and self-report surveys. Nevertheless, it appears that we have proven surprisingly resilient over time, with fast recovery from COVID-19 measures. Still, vulnerable groups such as adolescents and health care personnel that have been severely impacted by the COVID-19 pandemic do exist. Large interindividual differences exist, and for future pandemics there is a clear need to comprehensively and integratively assess resilience from the start to provide personalized help and interventions tailored to the specific needs for vulnerable groups.

Indexed as

COVID-19Population HealthResilience, PsychologicalAdolescentAgedChildFemaleHumansMental HealthPandemicsPregnancySARS-CoV-2

Identifiers

PMID34818601
PMCPMC8554139
OpenAlexW3211081783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.