Evidence map›Paper›PMID 34818519›Full record

ArticleCurrent biology : CB2022

Multisite phosphorylation by Cdk1 initiates delayed negative feedback to control mitotic transcription.

Jonathan B Asfaha, Mihkel Örd, Christopher R Carlson, Ilona Faustova, Mart Loog, David O Morgan

Open access · greenAbstract read
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. The molecular mechanisms of human separase regulation.Biochemical Society transactions · 2023
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jonathan B AsfahaDepartment of Physiology, University of California, San Francisco, San Francisco, USA.
Mihkel ÖrdInstitute of Technology, University of Tartu, Tartu, Estonia.
Christopher R CarlsonDepartment of Physiology, University of California, San Francisco, San Francisco, USA.
Ilona FaustovaInstitute of Technology, University of Tartu, Tartu, Estonia.
Mart LoogInstitute of Technology, University of Tartu, Tartu, Estonia.
David O MorganDepartment of Physiology, University of California, San Francisco, San Francisco, USA. Electronic address: david.morgan@ucsf.edu.
University of California, San Francisco · USUniversity of Tartu · EE

Funding

Regulatory Enzymes and Systems in Cell Cycle ControlR35GM118053 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAVID Owen MORGAN · 2016 to 2026
$10.3M
NIGMS NIH HHS R35 GM118053
6 · The paper itself

Abstract

Cell-cycle progression is driven by the phosphorylation of cyclin-dependent kinase (Cdk) substrates.

Indexed as

Saccharomyces cerevisiae ProteinsCDC2 Protein KinaseCell Cycle ProteinsCyclin BCyclinsFeedbackMitosisPhosphorylationSaccharomyces cerevisiaeTranscription FactorsCDC2 Protein KinaseCell Cycle ProteinsCyclin BCyclinsSaccharomyces cerevisiae ProteinsTranscription FactorsCdkcell cycleCks1Clb2cyclin gene expressionmultisite phosphorylationNdd1phosphodegron

Identifiers

PMID34818519
PMCPMC8752490
OpenAlexW3215569544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.