Evidence map›Paper›PMID 34818137›Full record

Observational studyScandinavian journal of primary health care2021

Antibiotic prescribing in Danish general practice in the elderly population from 2010 to 2017.

Maria Louise Veimer Jensen, Rune Munck Aabenhus, Barbara Juliane Holzknecht, Lars Bjerrum, Jette Nygaard Jensen, Volkert Siersma, Gloria Córdoba

Abstract readObservational Study
In one paragraph

Observational study in Scandinavian journal of primary health care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Clinical indications for antibiotic prescribing in Danish general practice.Scandinavian journal of primary health care · 2026
    Article
  2. Antibiotic treatment and antimicrobial resistance in urinary tract infections among the older population in Denmark, 1999 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Louise Veimer JensenDepartment of Clinical Microbiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0003-0355-6234
Rune Munck AabenhusThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9354-2236
Barbara Juliane HolzknechtDepartment of Clinical Microbiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0002-0320-5242
Lars BjerrumThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0969-0063
Jette Nygaard JensenDepartment of Clinical Microbiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID 0000-0001-5061-9766
Volkert SiersmaThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1941-2681
Gloria CórdobaThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-2609-0468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to describe prescription of antibiotics to the elderly population in general practice in Denmark from 2010-2017.

designThis is a national register-based observational study.

settingGeneral practice, Denmark.

main outcome measureThe main outcome measure was prescriptions/1,000 inhabitants/day (PrID) in relation to year, age and sex, indication, and antibiotic agent. SUBJECTS: In this study, we included inhabitants of Denmark, ≥65 years of age between 01st July 2010-30th June 2017.

resultsA total of 5,168,878 prescriptions were included in the study. Antibiotic prescriptions decreased from 2.2 PrID to 1.7 (-26.9%, CI95% [-31.1;-22.4]) PrID during the study. The decrease in PrID was most noticeable among 65-74-year-olds (-25%). The ≥85-year-olds were exposed to twice as many PrID than the 65-74-year-olds, but only accounted for 20% of the total use. Urinary tract infection (UTI) was the most common indication for antibiotic prescription and increased with advancing age. The most commonly prescribed antibiotics were pivmecillinam and phenoxymethylpenicillin. Prescribing with no informative indication was present in one third of all cases.

conclusionThe prescription of antibiotics in the elderly population in general practice decreased from 2010 to 2017. The oldest age group was exposed twice as frequently to antibiotic prescriptions as the 65-74-year-olds. The smallest reduction was observed for the ≥85-year-olds, suggesting targeting interventions at this group.Key PointsHigh antibiotic use among elderly is well known and studies indicate mis- and overuse within this population. Our study shows.The prescription rate is decreasing within all age groups of the elderly population.The ≥85-year-olds receive twice as many prescriptions/1000/day as the 65-74-years-olds.

Indexed as

Anti-Bacterial AgentsGeneral PracticeAgedAged, 80 and overDenmarkDrug PrescriptionsHumansInfantPractice Patterns, Physicians'Anti-Bacterial Agentsagedantibiotic prescriptionselderly populationGeneral practiceprescriptions patterns

Identifiers

PMID34818137
PMCPMC8725860

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.