Evidence map›Paper›PMID 34818035›Full record

ArticleScience advances2021

Scaling DNA data storage with nanoscale electrode wells.

Bichlien H Nguyen, Christopher N Takahashi, Gagan Gupta, Jake A Smith, Richard Rouse, Paul Berndt, Sergey Yekhanin, David P Ward, Siena D Ang, Patrick Garvan and 5 more

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Primer-Disk-Enabled DNA Data Storage System with Index and Record-Many-Read-Many Features.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Article
  9. DNA storage: The future direction for medical cold data storage.Synthetic and systems biotechnology · 2025
    Review
  10. Cost-Effective DNA Storage System with DNA Movable Type.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. "Cell Disk" DNA Storage System Capable of Random Reading and Rewriting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bichlien H NguyenMicrosoft Research, Redmond, WA, USA.ORCID 0000-0001-5870-4914
Christopher N TakahashiPaul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.
Gagan GuptaMicrosoft Research, Redmond, WA, USA.
Jake A SmithMicrosoft Research, Redmond, WA, USA.
Richard RouseMicrosoft Research, Redmond, WA, USA.
Paul BerndtMicrosoft Research, Redmond, WA, USA.
Sergey YekhaninMicrosoft Research, Redmond, WA, USA.
David P WardPaul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.ORCID 0000-0003-4829-0441
Siena D AngMicrosoft Research, Redmond, WA, USA.
Patrick GarvanMicrosoft Research, Redmond, WA, USA.ORCID 0000-0001-9510-4993
Hsing-Yeh ParkerMicrosoft Research, Redmond, WA, USA.
Rob CarlsonMicrosoft Research, Redmond, WA, USA.
Douglas CarmeanMicrosoft Research, Redmond, WA, USA.
Luis CezeMicrosoft Research, Redmond, WA, USA.ORCID 0000-0002-1377-6217
Karin StraussMicrosoft Research, Redmond, WA, USA.ORCID 0000-0002-8327-5477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic DNA is an attractive medium for long-term data storage because of its density, ease of copying, sustainability, and longevity. Recent advances have focused on the development of new encoding algorithms, automation, preservation, and sequencing technologies. Despite progress in these areas, the most challenging hurdle in deployment of DNA data storage remains the write throughput, which limits data storage capacity. We have developed the first nanoscale DNA storage writer, which we expect to scale DNA write density to 25 × 10

Identifiers

PMID34818035
PMCPMC8612674

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.