Evidence map›Paper›PMID 34818032›Full record

ArticleScience advances2021

Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.

Lisandro H Otero, Sabrina Foscaldi, Giuliano T Antelo, Germán L Rosano, Serena Sirigu, Sebastián Klinke, Lucas A Defelipe, Maximiliano Sánchez-Lamas, Giovanni Battocchio, Valeria Conforte and 6 more

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Circular dichroism spectroscopy reveals multiple phytochrome photoproducts in equilibrium.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
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  6. Xanthomonas campestris pv. campestris regulates virulence mechanisms by sensing blue light.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
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  12. Article
  13. The structural effect between the output module and chromophore-binding domain is a two-way street via the hairpin extension.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  14. Characterisation of sequence-structure-function space in sensor-effector integrators of phytochrome-regulated diguanylate cyclases.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  15. Article
  16. Cryo-Electron Microscopy ofFrontiers in plant science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lisandro H OteroFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0002-5448-5483
Sabrina FoscaldiFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0002-3502-0859
Giuliano T AnteloFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0001-6774-8812
Germán L RosanoUnidad de Espectrometría de Masa, Instituto de Biología Molecular y Celular de Rosario, UEM-IBR, CONICET, Bv. 27 de Febrero (S2000EZP), Rosario, Argentina.ORCID 0000-0002-8313-6813
Serena SiriguProxima-1, Synchrotron SOLEIL, L'Orme des Merisiers, Saint-Aubin, BP 48 (91192), Gif-sur-Yvette Cedex, France.ORCID 0000-0003-0875-5590
Sebastián KlinkeFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0002-8777-0870
Lucas A DefelipeEuropean Molecular Biology Laboratory (EMBL), Hamburg Unit, Notkestrasse 85 (22607), Hamburg, Germany.ORCID 0000-0001-7859-7300
Maximiliano Sánchez-LamasFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0003-0112-5641
Giovanni BattocchioTechnische Universität Berlin, Institute of Chemistry, Strasse des 17. Juni 135 (D-10623), Berlin, Germany.
Valeria ConforteInstituto de Ciencia y Tecnología Dr. César Milstein, Fundación Pablo Cassará, CONICET, Saladillo 2468 (C1440FFX), Buenos Aires, Argentina.
Adrián A VojnovInstituto de Ciencia y Tecnología Dr. César Milstein, Fundación Pablo Cassará, CONICET, Saladillo 2468 (C1440FFX), Buenos Aires, Argentina.ORCID 0000-0001-6238-6840
Leonard M G ChavasProxima-1, Synchrotron SOLEIL, L'Orme des Merisiers, Saint-Aubin, BP 48 (91192), Gif-sur-Yvette Cedex, France.ORCID 0000-0001-9973-9355
Fernando A GoldbaumFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.
Maria-Andrea MroginskiTechnische Universität Berlin, Institute of Chemistry, Strasse des 17. Juni 135 (D-10623), Berlin, Germany.ORCID 0000-0002-7497-5631
Jimena RinaldiFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0003-4088-7067
Hernán R BonomiFundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435 (C1405BWE), Buenos Aires, Argentina.ORCID 0000-0002-1550-6181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phytochromes constitute a widespread photoreceptor family that typically interconverts between two photostates called Pr (red light–absorbing) and Pfr (far-red light–absorbing). The lack of full-length structures solved at the (near-)atomic level in both pure Pr and Pfr states leaves gaps in the structural mechanisms involved in the signal transmission pathways during the photoconversion. Here, we present the crystallographic structures of three versions from the plant pathogen

Identifiers

PMID34818032
PMCPMC8612531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.