Evidence map›Paper›PMID 34817959›Full record

ArticleDimensions of critical care nursing : DCCN

Rapid Handheld Continuous Electroencephalogram (EEG) Has the Potential to Detect Delirium in Older Adults.

Malissa A Mulkey, Laura T Gantt, Sonya R Hardin, Cindy L Munro, D Erik Everhart, Sunghan Kim, Alexander M Schoeman, Donna W Roberson, Maura McAuliffe, DaiWai M Olson

Open access · greenAbstract read
In one paragraph

Article in Dimensions of critical care nursing : DCCN. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Review
  3. Bedside EEG for rapid diagnosis of delirium.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Malissa A Mulkey
Laura T Gantt
Sonya R Hardin
Cindy L Munro
D Erik Everhart
Sunghan Kim
Alexander M Schoeman
Donna W Roberson
Maura McAuliffe
DaiWai M Olson
Apple (Israel) · ILPearson (United States) · US

Funding

Advanced Training in Self-Management Interventions for Serious Chronic ConditionsT32NR018407 · NINR · INDIANA UNIVERSITY INDIANAPOLIS · PI KNOPF, AMELIA S, MILLER, WENDY RENEE · 2019 to 2023
$1.8M
NINR NIH HHS T32 NR018407
6 · The paper itself

Abstract

backgroundDelirium-related biochemical derangements lead to electrical changes that can be detected in electroencephalographic (EEG) patterns followed by behavioral signs and symptoms. Studies using limited lead EEG show a large difference between patients with and without delirium while discriminating delirium from other causes. Handheld rapid EEG devices may be capable of detecting delirium before symptom onset, thus providing an objective physiological method to detect delirium when it is most amenable to interventions.

objectiveThe aim of this study was to explore the potential for rapid EEG to detect waveform pattern changes consistent with delirium status.

methodsThis prospective exploratory pilot study used a correlational design and mixed models to explore the relationships between handheld portable EEG data and delirium status.

resultsWhile being under powered minimized opportunities to detect statistical differences in EEG-derived ratios using spectral density analysis, sleep-to-wake ratios tended to be higher in patients with delirium.

conclusionsLimited lead EEG may be useful in predicting adverse outcomes and risk for delirium in older critically ill patients. Although this population is at the highest risk for mortality, delirium is not easily identified by current clinical assessments. Therefore, further investigation of limited lead EEG for delirium detection is warranted.

Indexed as

DeliriumAgedCritical IllnessElectroencephalographyHumansPilot ProjectsProspective Studies

Identifiers

PMID34817959
PMCPMC8622342
OpenAlexW3216412661

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.