Evidence map›Paper›PMID 34817774›Full record

ArticleMolecular biology reports2022

Antineoplastic effectiveness of silver nanoparticles synthesized from Onopordum acanthium L. extract (AgNPs-OAL) toward MDA-MB231 breast cancer cells.

Romina Delalat, Seyed Ataollah Sadat Shandiz, Bahareh Pakpour

Abstract read
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Article in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Antibiotics (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Romina DelalatDepartment of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Seyed Ataollah Sadat ShandizDepartment of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran. Ata.sadatshandiz@iauctb.ac.ir.
Bahareh PakpourDepartment of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Islamic Azad University Central Tehran Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present research was done to investigate the anticancer properties of silver nanoparticles (AgNPs) fabricated using bioactive extract of Onopordum acanthium L. (AgNPs-OAL) against breast cancer cells MDA_MB231 in vitro.

methodsThe determination studies of AgNPs-OAL were confirmed by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) analysis. Interestingly, the FESEM image observed the spherical shape of AgNPs-OAL with the range of 1-100 nm.

resultsAs AgNP-OAL exhibited significant cytotoxicity properties on breast cancer MDA_MB231 cells with IC

conclusionsThe green-synthesized AgNP-OAL has promising anticancer efficiency that can trigger apoptosis pathways in the MDA_MB231 breast cancer cells.

Indexed as

Antineoplastic AgentsApoptosisBreast NeoplasmsCell CycleCell Line, TumorCell SurvivalFemaleGreen Chemistry TechnologyHEK293 CellsHumansMetal NanoparticlesOnopordumPlant ExtractsReactive Oxygen SpeciesSilverAntineoplastic AgentsPlant ExtractsReactive Oxygen SpeciesSilverAnticancerApoptosisReactive oxygen speciesSilver nanoparticles

Identifiers

PMID34817774
OpenAlexW3216584112

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.