Evidence map›Paper›PMID 34817650›Full record

ArticleDie Ophthalmologie2022

[Phacovitrectomy-Influence of the timing of intraocular lens implantation on the corneal endothelium].

Anastasia Seifert, Berthold Seitz, Gudrun Wagenpfeil, Klaus Ludwig, Matthias Krause

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Die Ophthalmologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Refraction and anatomical lens position predictability in phacovitrectomy using a 7 mm optic with cutout haptics versus a 6 mm optic with C-loop haptics.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Anastasia SeifertAugenklinik des Klinikums Fürth, Jakob-Henle-Str. 1, 90766, Fürth, Deutschland. a.seifert@osg.de.ORCID http://orcid.org/0000-0003-0619-2034
Berthold SeitzKlinik für Augenheilkunde, Universitätsklinikum des Saarlandes (UKS), Kirrberger Str. 100, 66424, Homburg, Deutschland.
Gudrun WagenpfeilInstitut für medizinische Biometrie, Epidemiologie und Medizinische Informatik (IMBEI), Universität des Saarlandes, Kirrberger Str. 100, 66424, Homburg, Deutschland.
Klaus LudwigAugenklinik des Klinikums Fürth, Jakob-Henle-Str. 1, 90766, Fürth, Deutschland.
Matthias KrauseAugenklinik des Klinikums Fürth, Jakob-Henle-Str. 1, 90766, Fürth, Deutschland.
Nuremberg Hospital · DEUniversitätsklinikum des Saarlandes · DEInstitut für Medizinische Biometrie, Informatik und Epidemiologie · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIn phacovitrectomy the cataract is usually operated on first including implantation of the intraocular lens (IOL) before beginning vitrectomy but the IOL can also be implanted following vitrectomy. This variation avoids optical impairments from corneal opacities and the lens rim, improves the visualization of the retina during surgery and might thereby reduce intraoperative complications, such as peripheral retinal tears or IOL subluxation. It might, however, increase stress on the corneal endothelium. The aim of this study was, therefore, to compare postoperative corneal endothelial cell loss for the standard procedure of phacovitrectomy and the surgical variation.

methodsIn this retrospective study 41 eyes were each assigned to group I (standard phacovitrectomy) or group II (variation of phacovitrectomy). The primary endpoint was the absolute and relative corneal endothelial cell loss appearing 5 ± 1 weeks postoperatively with reference to the preoperative number of endothelial cells. Secondary endpoints included visual acuity, intraocular pressure, coefficient of variation of endothelial cell area (CV), proportion of hexagonal endothelial cell forms (6A), pachymetry, intraoperative and postoperative complications.

resultsThe absolute and relative endothelial cell loss in group I (-108 ± 146; -4.1 ± 5.7%) did not differ significantly from that in group II (-73 ± 122; -3.1 ± 5.3%, p = 0.299; p = 0.388). The secondary endpoints also showed no significant differences.

conclusionThe presented variation of phacovitrectomy expands the surgical options and does not show a significantly different postoperative corneal endothelial cell loss compared to the standard procedure.

Indexed as

Endothelium, CornealLens Implantation, IntraocularCorneal Endothelial Cell LossEndothelial CellsHumansRetrospective StudiesCoefficient of variation of cell area (CV)Endothelial cell lossPachymetryPhacovitrectomyProportion of hexagonal cells (6A%)

Identifiers

PMID34817650
OpenAlexW3214997737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.