Evidence map›Paper›PMID 34817230›Full record

ArticleMicrobiology spectrum2021

Prevalence, Risk Factors, and Molecular Epidemiology of Intestinal Carbapenem-Resistant Pseudomonas aeruginosa.

Yanyan Hu, Yan Qing, Jiawei Chen, Congcong Liu, Jiayue Lu, Qi Wang, Shufang Zhen, Hongwei Zhou, Ling Huang, Rong Zhang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Enhanced Spread of Carbapenem-ResistantInfection and drug resistance · 2026
    Article
  7. Review
  8. Article
  9. [Clinical characteristics and risk factors of carbapenem-resistantZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  10. Review
  11. Review
  12. KPC-2-producing Pseudomonas aeruginosa isolated from wild animals in Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Comparison ofMicrobiology spectrum · 2023
    Article
  17. Worldwide Dissemination ofAntibiotics (Basel, Switzerland) · 2023
    Review
  18. Carbapenem-resistantFrontiers in public health · 2023
    Article
  19. A comparative study of intestinalOne health advances · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yanyan Hu *Clinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Yan Qing *Clinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Jiawei ChenClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Congcong LiuClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Jiayue LuClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Qi WangClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Shufang ZhenDepartment of Clinical Laboratory, Jinhua People's Hospital, Jinhua, China.
Hongwei ZhouClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.ORCID 0000-0002-9478-4023
Ling HuangClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Rong ZhangClinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CNHangzhou Women’s Hospital · CNJinhua Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa may become multidrug-resistant (MDR) due to multiple inherited and acquired resistance mechanisms. The human gastrointestinal tract is known as a reservoir of P. aeruginosa and its resistance genes. In this study, we collected 76 intestinal carbapenem-resistant P. aeruginosa (CRPA) strains from clinical inpatients admitted to our hospital from 2014 to 2019, together with their medical data. We aim to analyze the clinical risk factors associated with CRPA infection and its molecular features. We found that the prevalence of CRPA in P. aeruginosa strains was 41.3% (95% confidence interval [CI], 34.1 to 48.8%). We also identified four variables associated with intestinal CRPA positivity, prior antibiotic exposure to aminoglycosides or carbapenems, underlying diabetes mellitus, and extraintestinal P. aeruginosa isolation.

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsChinaCross InfectionDrug Resistance, Multiple, BacterialGastrointestinal MicrobiomeGenome, BacterialHumansInterspersed Repetitive SequencesIntestinesMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyPrevalenceAnti-Bacterial AgentsBacterial Proteinsbeta-lactamase KPC-2beta-LactamasescarbapenemaseCarbapenemsclinical characteristicsCRPAKPCprevalencePseudomonas aeruginosarisk factors

Identifiers

PMID34817230
PMCPMC8612150
OpenAlexW3216798099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.