Evidence map›Paper›PMID 34817128›Full record

ArticleThe plant genome2021

Accelerating wheat breeding for end-use quality through association mapping and multivariate genomic prediction.

Shichen Zhang-Biehn, Allan K Fritz, Guorong Zhang, Byron Evers, Rebecca Regan, Jesse Poland

Open access · goldAbstract read
In one paragraph

Article in The plant genome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Evaluating reaction norm and fixed effect models for genomic selection of end-use quality in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  6. Improved bivariate analysis of canola survivability against blackleg disease.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
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  9. Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2024
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  11. The Genetic Dissection of Nitrogen Use-Related Traits in Flax (International journal of molecular sciences · 2023
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Shichen Zhang-BiehnDep. of Plant Pathology, Kansas State Univ., 4024 Throckmorton Plant Sciences Center, 1712 Claflin Rd., Manhattan, KS, 66506, USA.ORCID 0000-0002-3992-7810
Allan K FritzDep. of Agronomy, Kansas State Univ., 4012 Throckmorton Plant Sciences Center, 1712 Claflin Rd., Manhattan, KS, 66506, USA.ORCID 0000-0003-2574-8675
Guorong ZhangAgricultural Research Center-Hays, Kansas State Univ., 1232 240th Ave., Hays, KS, 67601, USA.
Byron EversDep. of Plant Pathology, Kansas State Univ., 4024 Throckmorton Plant Sciences Center, 1712 Claflin Rd., Manhattan, KS, 66506, USA.ORCID 0000-0003-1840-5842
Rebecca ReganDep. of Grain Science and Industry, Kansas State Univ., Shellenberger 108, Manhattan, KS, 66506, USA.
Jesse PolandDep. of Plant Pathology, Kansas State Univ., 4024 Throckmorton Plant Sciences Center, 1712 Claflin Rd., Manhattan, KS, 66506, USA.ORCID 0000-0002-7856-1399
Kansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In hard-winter wheat (Triticum aestivum L.) breeding, the evaluation of end-use quality is expensive and time-consuming, being relegated to the final stages of the breeding program after selection for many traits including disease resistance, agronomic performance, and grain yield. In this study, our objectives were to identify genetic variants underlying baking quality traits through genome-wide association study (GWAS) and develop improved genomic selection (GS) models for the quality traits in hard-winter wheat. Advanced breeding lines (n = 462) from 2015-2017 were genotyped using genotyping-by-sequencing (GBS) and evaluated for baking quality. Significant associations were detected for mixograph mixing time and bake mixing time, most of which were within or in tight linkage to glutenin and gliadin loci and could be suitable for marker-assisted breeding. Candidate genes for newly associated loci are phosphate-dependent decarboxylase and lipid transfer protein genes, which are believed to affect nitrogen metabolism and dough development, respectively. The use of GS can both shorten the breeding cycle time and significantly increase the number of lines that could be selected for quality traits, thus we evaluated various GS models for end-use quality traits. As a baseline, univariate GS models had 0.25-0.55 prediction accuracy in cross-validation and from 0 to 0.41 in forward prediction. By including secondary traits as additional predictor variables (univariate GS with covariates) or correlated response variables (multivariate GS), the prediction accuracies were increased relative to the univariate model using only genomic information. The improved genomic prediction models have great potential to further accelerate wheat breeding for end-use quality.

Indexed as

Plant BreedingTriticumGenome-Wide Association StudyGenomicsQuantitative Trait Loci

Identifiers

PMID34817128
PMCPMC12807266
OpenAlexW3217091707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.