Evidence map›Paper›PMID 34817024›Full record

ArticleActa cirurgica brasileira2021

Effect of low-level laser therapy on the membrane induced by the Masquelet technique at an orthotopic site in rabbits.

Jeniffer Gabriela Figueroa Coris, Sheila Canevese Rahal, Carlos Eduardo Fonseca-Alves, Maria Jaqueline Mamprim, Letícia Rocha Inamassu, Alexandre Botelho de Abreu Sampaio, Washington Takashi Kano, Luciane Dos Reis Mesquita, José Ivaldo de Siqueira Silva Junior

Open access · goldAbstract read
In one paragraph

Article in Acta cirurgica brasileira, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jeniffer Gabriela Figueroa CorisMSc. Postgraduate Program in Animal Biotechnology - Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-1757-5682
Sheila Canevese RahalMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-9211-4093
Carlos Eduardo Fonseca-AlvesMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-6702-6139
Maria Jaqueline MamprimMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-2238-5584
Letícia Rocha InamassuMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-7528-3311
Alexandre Botelho de Abreu SampaioMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0001-8819-728X
Washington Takashi KanoMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-6574-6108
Luciane Dos Reis MesquitaMSc, PhD. Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0003-3853-7084
José Ivaldo de Siqueira Silva JuniorMSc. Postgraduate Program in Animal Biotechnology - Department of Veterinary Surgery and Animal Reproduction - School of Veterinary Medicine and Animal Science - Universidade Estadual Paulista (UNESP) - Botucatu (SP), Brazil.ORCID http://orcid.org/0000-0002-8758-0647
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the low-level laser therapy (LLLT) on the membrane induced by the Masquelet technique in rabbits.

methodsTwelve Norfolk rabbits at approximately 3 months of age were used. A 1-cm segmental defect was induced in both radii, which were filled with polymethylmethacrylate cylinder. LLLT was used postoperatively in the bone defect of one of the forelimbs every 48 hours for 15 days. Six rabbits were euthanatized on third and sixth postoperative weeks.

resultsIn both forelimbs, radiographs showed new bone growth from radius cut ends on the third postoperative week and more advanced stage on the sixth postoperative week. Ultrasound showed induced membrane one week after the surgery. Histologically, there were no significant differences in the semi-quantitative score of inflammation intensity, total number of blood vessels, bone metaplasia, and collagen. The average thicknesses were 2,050.17 and 1,451.96 μm for control membranes and 2,724.26 and 2,081.03 μm for irradiated membranes, respectively, on third and sixth postoperative weeks. Vascular endothelial growth factor A (VEGF-A) and platelet derived growth factor (PDGF) expression were present in the induced membranes of control and irradiated forelimbs, but there was no significant difference.

conclusionsBased on assessment methods, it was not possible to demonstrate the effect of LLLT on the induced membrane.

Indexed as

Low-Level Light TherapyVascular Endothelial Growth Factor AAnimalsBone and BonesCollagenRabbitsCollagenVascular Endothelial Growth Factor A

Identifiers

PMID34817024
PMCPMC8610207
OpenAlexW3217302263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.