ArticleArquivos de neuro-psiquiatria2022
Cognitive consequences of COVID-19: results of a cohort study from South America.
Article in Arquivos de neuro-psiquiatria, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 6 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 6 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Meta-analysis of Cognitive Function Following Non-severe SARS-CoV-2 Infection.Neuropsychology review · 2025Pooled it
- Neurocognitive Impairment in Long COVID: A Systematic Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Pooled it
- Cognitive domains affected post-COVID-19; a systematic review and meta-analysis.European journal of neurology · 2025Pooled it
- Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19.Behavioural neurology · 2023Pooled it
- COVID-19 associated cognitive impairment: A systematic review.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Pooled it
- Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Pooled it
- Subjective and objective working memory deficits in the post-acute phase of COVID-19 in a clinical trial population.Brain, behavior, & immunity - health · 2026Article
- Prior COVID-19 vaccination and cognitive outcomes after SARS-CoV-2 infection: a mini-review.Dementia & neuropsychologia · 2026Review
- First episode of psychiatric and neuropsychiatric disease among patients infected with COVID-19: A scoping review.PCN reports : psychiatry and clinical neurosciences · 2025Review
- Correlation Between COVID-19 Recovery, Executive Function Decline, and Emotional State.Psychology research and behavior management · 2025Article
- Long COVID among Brazilian Adults and Elders 12 Months after Hospital Discharge: A Population-Based Cohort Study.Healthcare (Basel, Switzerland) · 2024Article
- Cognitive performance of post-covid patients in mild, moderate, and severe clinical situations.BMC psychology · 2024Article
- Procedural Motor Memory Deficits in Patients With Long-COVID.Neurology · 2024Article
- Long COVID: neurological manifestations - an updated narrative review.Dementia & neuropsychologia · 2024Review
- Neurologic manifestations of Long COVID in Colombia: a comparative analysis of post-hospitalization vs. non-hospitalized patients.Frontiers in human neuroscience · 2024Article
- Management of cognitive impairment associated with post-COVID-19 syndrome: recommendations for primary care.Frontiers in pharmacology · 2024Review
- Cognitive impairment and neuropsychiatric symptoms among individuals with history of symptomatic SARS-CoV-2 infection: a retrospective longitudinal study.Dementia & neuropsychologia · 2024Article
- Memory, Emotion, and Quality of Life in Patients with Long COVID-19.Brain sciences · 2023Article
- Cognitive impairment in post-acute COVID-19 syndrome: a scoping review.Arquivos de neuro-psiquiatria · 2023Article
- [Cognitive alterations in patients recovered from COVID-19 treated in Cardiopulmonary Rehabilitation].Revista medica del Instituto Mexicano del Seguro Social · 2023Observational
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeurological and psychiatric manifestations associated with SARS-CoV-2 infection have been reported throughout the scientific literature. However, studies on post-COVID cognitive impairment in people with no previous cognitive complaint are scarce.
objectiveWe aim to investigate the impact of COVID-19 on cognitive functions in adults without cognitive complaints before infection and to study cognitive dysfunction according to disease severity and cognitive risk factors.
methodsForty-five post-COVID-19 patients and forty-five controls underwent extensive neuropsychological evaluation, which assessed cognitive domains such as memory, language, attention, executive functions, and visuospatial skills, including psychiatric symptomatology scales. Data were collected on the severity of infection, premorbid medical conditions, and functionality for activities of daily living before and after COVID-19.
resultsSignificant differences between groups were found in cognitive composites of memory (p=0.016, Cohen's d= 0.73), attention (p<0.001, Cohen's d=1.2), executive functions (p<0.001, Cohen's d=1.4), and language (p=0.002, Cohen's d=0.87). The change from premorbid to post-infection functioning was significantly different between severity groups (WHODAS, p=0.037). Self-reported anxiety was associated with the presence of cognitive dysfunction in COVID-19 subjects (p=0.043).
conclusionOur results suggest that the presence of cognitive symptoms in post-COVID-19 patients may persist for months after disease remission and argue for the inclusion of cognitive assessment as a protocolized stage of the post-COVID examination. Screening measures may not be sufficient to detect cognitive dysfunction in post-COVID-19 patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.