ArticleThe Journal of organic chemistry2021
Synthesis of Rhodamines and Rosamines Using 3,6-Difluoroxanthone as a Common Intermediate.
Article in The Journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A general strategy towards multicolour fluorogenic peptides for wash-free bioassays.Nature chemistry · 2026Article
- Rosamine derivatives ofOrganic & biomolecular chemistry · 2026Article
- Controlling Intramolecular Rotation with Five-Membered Heterocycles Facilitates the Design of Highly Cell-Permeable Xanthene-Based Fluorogenic Probes.Journal of the American Chemical Society · 2025Article
- Supramolecular Complexation of Quenched Rosamines with Cucurbit[7]Uril: Fluorescence Turn-ON Effect for Super-Resolution Imaging.Journal of the American Chemical Society · 2025Article
- Improving the Brightness of Pyronin Fluorophore Systems through Quantum-Mechanical Predictions.The journal of physical chemistry letters · 2022Article
- Synthesis of a fluorinated pyronin that enables blue light to rapidly depolarize mitochondria.RSC medicinal chemistry · 2022Article
- Functionalization of Rhodamine Platforms with 3-Hydroxy-4-pyridinone Chelating Units and Its Fluorescence Behavior towards Fe(III).Molecules (Basel, Switzerland) · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
Rhodamines and structurally similar rosamines are some of the most highly utilized tools for molecular imaging experiments. We report a general and high-yielding route to produce 18 examples of rhodamines and rosamines, including tetramethylrhodamine, rhodamine B, and Janelia Fluor 549, from a single xanthone intermediate, 3,6-difluoroxanthone. Spectroscopic studies revealed trends in fluorophore efficiency based on substitution patterns at the 3'-, 6'-, and 9'-positions, providing insights to aid future designs of rhodamines/rosamines.
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Registered trials
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