Evidence map›Paper›PMID 34816629›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Nanomotor-Derived Porous Biomedical Particles from Droplet Microfluidics.

Yuxiao Liu, Yi Cheng, Cheng Zhao, Huan Wang, Yuanjin Zhao

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Microfluidics-Based Microcarriers for Live-Cell Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Nanomedicine for Diagnosis and Treatment of Atherosclerosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  7. Article
  8. Size tunable fabrication of magnetic alginate microparticles using flow focusing microfluidics.Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems · 2023
    Article
  9. Sunset Yellow Confined in Curved Geometry: A Microfluidic Approach.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  10. Arthritic Microenvironment Actuated Nanomotors for Active Rheumatoid Arthritis Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  11. Review
  12. Nanomotor-Derived Porous Biomedical Particles from Droplet Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuxiao LiuDepartment of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China.ORCID 0000-0001-9450-3730
Yi ChengDepartment of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China.
Cheng ZhaoDepartment of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China.
Huan WangState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Yuanjin ZhaoDepartment of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China.ORCID 0000-0001-9242-4000
Nanjing Drum Tower Hospital · CNState Key Laboratory of Digital Medical Engineering

Funding

National Key Research and Development Program of China 2020YFA0908200National Natural Science Foundation of China 52073060National Natural Science Foundation of China 61927805Shenzhen Fundamental Research Program JCYJ20190813152616459
6 · The paper itself

Abstract

Porous particles have found widespread applications in therapeutic diagnosis, drug delivery, and tissue engineering due to their typical properties of large surface area, extensive loading capacity, and hierarchical microstructures. Attempts in this aspect are focusing on the development of effective methods to generate functional porous particles. Herein, a simple droplet microfluidics for continuously and directly generating porous particles by introducing bubble-propelled nanomotors into the system is presented. As the nanomotors can continuously generate gas bubbles in the unsolidified droplet templates, the desirable porous microparticles can be obtained after droplet polymerization. It is demonstrated that the generation process is highly controlled and the resultant microparticles show excellent porosity and monodispersity. In addition, the obtained porous microparticles can serve as microcarriers for 3D cell culture, because of their characteristic porous structures and favorable biocompatibility. Moreover, owing to the existence of oxygen in these microparticles, they can be used to improve the healing effects of wounds in the type I diabetes rat models. These remarkable features of the generation strategy and the porous microparticles point to their potential values in various biomedical fields.

Indexed as

Lab-On-A-Chip DevicesNanostructuresWound HealingAnimalsCell Culture TechniquesDiabetes Mellitus, ExperimentalDisease Models, AnimalMicrofluidicsNanoparticlesPorosityRatsRats, Sprague-DawleyTissue Engineeringcell culturedropletmicrofluidicsnanomotorsporous microparticleswound healing

Identifiers

PMID34816629
PMCPMC8811803
OpenAlexW3216189164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.