Evidence map›Paper›PMID 34816409›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Testing Novel Inactivation Methods and Adjuvants for Vaccines Against Streptococcus agalactiae in Nile Tilapia Oreochromis niloticus.

Fernando Carlos Ramos-Espinoza, Victor Alexander Cueva-Quiroz, Jefferson Yunis-Aguinaga, Norquis Caled Alvarez-Rubio, Nicoli Paganoti de Mello, Julieta Rodini Engrácia de Moraes

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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Duration of Protection and Humoral Immune Response in Nile Tilapia (Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fernando Carlos Ramos-EspinozaAquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil. fernando.ramos@unesp.br.
Victor Alexander Cueva-QuirozAquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil.
Jefferson Yunis-AguinagaAquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil.
Norquis Caled Alvarez-RubioAquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil.
Nicoli Paganoti de MelloAquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil.
Julieta Rodini Engrácia de MoraesAquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inactivation by hydrogen peroxide and pH manipulation are two novel methods used recently in experimental vaccines against Streptococcus agalactiae in Nile tilapia. Here we describe in detail inactivation using novel methods as well as the classical method of inactivation. These vaccines showed similar moderate efficacy when compared to the conventional formaldehyde vaccine. In addition, we describe the inclusion of adjuvants in a hydrogen peroxide vaccine.

Indexed as

CichlidsFish DiseasesStreptococcal InfectionsStreptococcal VaccinesStreptococcus agalactiaeAdjuvants, ImmunologicAnimalsHydrogen PeroxideAdjuvants, ImmunologicHydrogen PeroxideStreptococcal VaccinesAluminum hydroxideBacterial inactivationHydrogen peroxideStreptococcosisVaccination

Identifiers

PMID34816409
OpenAlexW3216261669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.