Evidence map›Paper›PMID 34816399›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Reverse Genetics and Its Usage in the Development of Vaccine Against Poultry Diseases.

Barnali Nath, Sudhir Morla, Sachin Kumar

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Barnali NathDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India.
Sudhir MorlaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India.
Sachin KumarDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India. sachinku@iitg.ac.in.
Indian Institute of Technology Guwahati · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines are the most effective and economic way of combating poultry viruses. However, the use of traditional live-attenuated poultry vaccines has problems such as antigenic differences with the currently circulating strains of viruses and the risk of reversion to virulence. In veterinary medicine, reverse genetics is applied to solve these problems by developing genotype-matched vaccines, better attenuated and effective live vaccines, broad-spectrum vaccine vectors, bivalent vaccines, and genetically tagged recombinant vaccines that facilitate the serological differentiation of vaccinated animals from infected animals. In this chapter, we discuss reverse genetics as a tool for the development of recombinant vaccines against economically devastating poultry viruses.

Indexed as

AnimalsAntibodies, ViralChickensPoultryPoultry DiseasesReverse GeneticsVaccines, AttenuatedVaccines, SyntheticViral VaccinesAntibodies, ViralVaccines, AttenuatedVaccines, SyntheticViral VaccinesAvian coronavirusAvian influenzaNewcastle diseasePoultryReverse geneticsVaccines

Identifiers

PMID34816399
OpenAlexW3217047757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.