SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022
The effect of music therapy on language recovery in patients with aphasia after stroke: a systematic review and meta-analysis.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Potential benefits of music-based therapies on rehabilitation outcomes in people with multiple sclerosis: a systematic review.BMJ open · 2026Pooled it
- Effects of music-based interventions on rehabilitation outcomes after stroke: a systematic review and meta-analysis of randomized controlled trials.Frontiers in neurology · 2026Pooled it
- Structural and functional neuroplasticity in music and dance-based rehabilitation: a systematic review.Journal of neurology · 2025Pooled it
- Effect of three rehabilitation methods combined with transcranial electromagnetic stimulation on post-stroke aphasia: a RCT network meta-analysis.Frontiers in neurology · 2025Pooled it
- Efficacy and safety of repetitive transcranial magnetic therapy for post-stroke aphasia: a systematic review and meta-analysis of randomized controlled trials.Frontiers in neurology · 2025Pooled it
- Effects of Music Therapy on Aphasia and Cognition of Patients with Post-stroke: A Systematic Review and Meta-analysis.Noise & healthPooled it
- Review
- Transcranial Magnetic Stimulation Combined with Speech-Language Therapy for Post-Stroke Aphasia Recovery: A Systematic Review and Network Meta-Analysis.Therapeutics and clinical risk management · 2026Review
- Article
- A Systematic Scoping Review of Measures Used to Evaluate Treatment-Induced Changes in Depression, Anxiety, and Chronic Stress in People with Post-Stroke Aphasia.Aphasiology · 2025Article
- Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review).Frontiers in human neuroscience · 2025Review
- Transforming text to music using artificial intelligence improves the frontal lobe function of normal older adults.Brain and behavior · 2024Article
- Oxytocin as a physiological correlate of dyadic music therapy relationships - a randomized crossover pilot study.Frontiers in behavioral neuroscience · 2024Article
- Meta-analysis of clinical efficacy of acupuncture and moxibustion in rehabilitation treatment for post-stroke aphasia.American journal of translational research · 2024Review
- Soothe the savage beast: Patient perceptions of the benefits of music therapy in an inpatient rehabilitation facility.PM & R : the journal of injury, function, and rehabilitation · 2023Article
- Music Therapy in Global Aphasia: A Case Report.Medicines (Basel, Switzerland) · 2023Article
- Efficacy of a multicomponent singing intervention on communication and psychosocial functioning in chronic aphasia: a randomized controlled crossover trial.Brain communications · 2023Article
- Potential Benefits of Music Therapy on Stroke Rehabilitation.Oxidative medicine and cellular longevity · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this meta-analysis was to evaluate the evidence on the effectiveness of music therapy in the recovery of language function in post-stroke aphasia, compared with conventional therapy or no therapy.
methodsWe searched studies that explored the effect of music therapy on language function in post-stroke aphasia and published in PubMed, Embase, the Cochrane Library, Web of Science, CINAHL, ProQuest Digital Dissertations, and ClinicalTrials.gov from inception to March 2021. Six reviewers independently screened out eligible studies, extracted data, and evaluated the methodological quality. Results were pooled using mean difference (MD) with 95% confidence interval (CI). Heterogeneity was assessed by the chi-square test and I
resultsSix studies were included in this meta-analysis involving 115 patients. The methodological quality of these studies ranged from poor to excellent. There was significant mean difference in functional communication for post-stroke aphasia by 1.45 (95% CI: 0.24, 2.65; P = 0.02, from poor to excellent evidence), in repetition by 6.49 (95% CI: 0.97, 12.00; P = 0.02, from acceptable to excellent evidence), and in naming by 11.44 (95% CI: 1.63, 21.26; P = 0.02, from acceptable to excellent evidence). But there was no significant difference in comprehension for post-stroke aphasia by 7.21 (95% CI: - 10.88, 25.29; P = 0.43, from acceptable to excellent evidence).
conclusionsMusic therapy can improve functional communication, repetition, and naming in patients with post-stroke aphasia, but did not significantly improve comprehension.
trial registrationCRD42021251526.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.