Evidence map›Paper›PMID 34816263›Full record

ArticlebioRxiv : the preprint server for biology2021

#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol.

Abigail Dommer, Lorenzo Casalino, Fiona Kearns, Mia Rosenfeld, Nicholas Wauer, Surl-Hee Ahn, John Russo, Sofia Oliveira, Clare Morris, Anthony Bogetti and 42 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

52 authors.

Abigail DommerUC San Diego.
Lorenzo CasalinoUC San Diego.
Fiona KearnsUC San Diego.
Mia RosenfeldUC San Diego.
Nicholas WauerUC San Diego.
Surl-Hee AhnUC San Diego.
John RussoOregon Health & Science University.
Sofia OliveiraUniversity of Bristol.
Clare MorrisUC San Diego.
Anthony BogettiUniversity of Pittsburgh.
Anda TrifanArgonne National Laboratory.
Alexander BraceArgonne National Laboratory.
Terra SztainUC San Diego.
Austin ClydeArgonne National Laboratory.
Heng MaArgonne National Laboratory.
Chakra ChennubhotlaUniversity of Pittsburgh.
Hyungro LeeBrookhaven National Lab & Rutgers University.
Matteo TurilliBrookhaven National Lab & Rutgers University.
Syma KhalidUniversity of Oxford.
Teresa Tamayo-MendozaEntos, Inc.
Matthew WelbornEntos, Inc.
Anders ChristensenEntos, Inc.
Daniel G A SmithEntos, Inc.
Zhuoran QiaoCalifornia Institute of Technology.
Sai Krishna SirumallaEntos, Inc.
Michael O'ConnorEntos, Inc.
Frederick ManbyEntos, Inc.
Anima AnandkumarCalifornia Institute of Technology.
David HardyUniversity of Illinois at Urbana-Champaign.
James PhillipsUniversity of Illinois at Urbana-Champaign.
Abraham SternNVIDIA Corporation.
Josh RomeroNVIDIA Corporation.
David ClarkNVIDIA Corporation.
Mitchell DorrellPittsburgh Supercomputing Center.
Tom MaidenPittsburgh Supercomputing Center.
Lei HuangTexas Advanced Computing Center.
John McCalpinTexas Advanced Computing Center.
Christopher WoodsUniversity of Bristol.
Alan GrayNVIDIA Corporation.
Matt WilliamsUniversity of Bristol.
Bryan BarkerOracle for Research.
Harinda RajapakshaOracle for Research.
Richard PittsOracle for Research.
Tom GibbsNVIDIA Corporation.
John StoneUniversity of Illinois at Urbana-Champaign.
Daniel ZuckermanOregon Health & Science University.
Adrian MulhollandUniversity of Bristol.
Thomas MillerEntos, Inc.
Shantenu JhaBrookhaven National Lab & Rutgers University.
Arvind RamanathanArgonne National Laboratory.
Lillian ChongUniversity of Pittsburgh.
Rommie AmaroUC San Diego.

Funding

WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TAJKHORSHID, EMAD · 2012 to 2021
$19.0M
Training in Multi-Scale Analysis of Biological Structure and FunctionT32EB009380 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrew D. McCulloch, Padmini Rangamani · 2009 to 2026
$4.8M
WESTPA: A high-performance framework for simulating at the frontiers of biologyR01GM115805 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LILLIAN T CHONG · 2015 to 2026
$4.0M
A MULTISCALE APPROACH TO TARGET THE ACHILLES HEEL OF P53 CANCER MUTANTS (Equipment Supplement)R01GM132826 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2019 to 2022
$1.3M
NIBIB NIH HHS T32 EB009380NIGMS NIH HHS P41 GM104601NIGMS NIH HHS R01 GM115805NIGMS NIH HHS R01 GM132826
6 · The paper itself

Abstract

We seek to completely revise current models of airborne transmission of respiratory viruses by providing never-before-seen atomic-level views of the SARS-CoV-2 virus within a respiratory aerosol. Our work dramatically extends the capabilities of multiscale computational microscopy to address the significant gaps that exist in current experimental methods, which are limited in their ability to interrogate aerosols at the atomic/molecular level and thus ob-scure our understanding of airborne transmission. We demonstrate how our integrated data-driven platform provides a new way of exploring the composition, structure, and dynamics of aerosols and aerosolized viruses, while driving simulation method development along several important axes. We present a series of initial scientific discoveries for the SARS-CoV-2 Delta variant, noting that the full scientific impact of this work has yet to be realized. ACM REFERENCE FORMAT: Abigail Dommer

Identifiers

PMID34816263
PMCPMC8609898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.