ReviewFrontiers in global women's health2021
Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence.
Review in Frontiers in global women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Patient characteristics and lifestyle determinants of quality of life among women with endometriosis: a systematic review.Reproduction & fertility · 2026Pooled it
- Dietary Supplements for Endometriosis-Associated Pain: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.Gynecologic and obstetric investigation · 2026Pooled it
- The natural evolution of untreated deep endometriosis and the effect of hormonal suppression: A systematic literature review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
- Linzagolix therapy versus a placebo in patients with endometriosis-associated pain: a prospective, randomized, double-blind, Phase 3 study (EDELWEISS 3).Human reproduction (Oxford, England) · 2024Trial
- Medical and Surgical Management of Endometriosis: A Narrative Review of Clinical Outcomes.Cureus · 2026Review
- Article
- Current Insights into Endometriosis: Hormonal Management, Clinical Outcomes, and Opportunities for Progress.Current pharmaceutical design · 2026Review
- Linzagolix, with and without add-back therapy, in women with endometriosis-associated pain: results from EDELWEISS 6, a double-blind randomized extension and withdrawal study.Human reproduction open · 2026Article
- Barriers affecting medication adherence to dienogest among patients with ovarian endometriosis: a qualitative study.Frontiers in medicine · 2026Article
- Comparison of quality of life in patients with endometriosis undergoing treatment with progestins, oral contraceptives pills (OCP), and GnRH agonists.BMC women's health · 2025Observational
- Knowledge, attitudes, and practices of patients with endometriosis regarding endometriosis surgery and postoperative care in Liaoning Province, China: a cross-sectional analysis.BMC pregnancy and childbirth · 2025Article
- Prediction of genomic biomarkers for endometriosis using the transcriptomic dataset.World journal of clinical cases · 2025Article
- Prevalence of anhedonia in women with deep endometriosis.Scientific reports · 2025Article
- Targeting angiogenesis in endometriosis: a systematic review and network meta-analysis of VEGF-directed pharmacotherapies.Frontiers in reproductive health · 2025Article
- Review
- Review
- Article
- Article
- Article
- Horizons in Endometriosis: Proceedings of the Montreux Reproductive Summit, 14-15 July 2023.Facts, views & vision in ObGyn · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is associated with painful symptoms, infertility, sexological difficulties, and psychological suffering. All these symptoms have a negative impact on the overall quality of life of women with the disease, with significant personal, social and economic costs. Several medical options are available to manage symptomatic endometriosis. The pharmacological treatment for endometriosis-related pain may be necessary for decades, or at least until there is a desire for pregnancy or physiologic menopause occurs. In this perspective, clinicians should consider not only the efficacy, but also side effects, tolerability, and costs, along with women's preferences toward different treatments. In this mini-review, we analyzed the pros and cons of the available drugs for the medical therapy of endometriosis, such as estrogen-progestins, progestins, GnRH agonist and GnRH antagonists.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.