Evidence map›Paper›PMID 34816129›Full record

ArticleSTAR protocols2021

A protocol for the induction of experimental necrotizing enterocolitis in neonatal mice.

Lila S Nolan, Qingqing Gong, Heather N Hofmeister, Misty Good

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. An anti-eCIRP strategy for necrotizing enterocolitis.Molecular medicine (Cambridge, Mass.) · 2024
    Article
  6. Article
  7. Article
  8. The Role of the Interleukin-1 Family in Complications of Prematurity.International journal of molecular sciences · 2023
    Review
  9. Review
  10. Review
  11. In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis.Journal of visualized experiments : JoVE · 2022
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lila S NolanDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis Children's Hospital, 660 S. Euclid Avenue, Campus Box 8208, St. Louis, MO 63110, USA.
Qingqing GongDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis Children's Hospital, 660 S. Euclid Avenue, Campus Box 8208, St. Louis, MO 63110, USA.
Heather N HofmeisterDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis Children's Hospital, 660 S. Euclid Avenue, Campus Box 8208, St. Louis, MO 63110, USA.
Misty GoodDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis Children's Hospital, 660 S. Euclid Avenue, Campus Box 8208, St. Louis, MO 63110, USA.
St. Louis Children's Hospital · US

Funding

Non-invasive analysis of methylated cell free DNA in necrotizing enterocolitisR01DK124614 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L, PETERS, DAVID GERARD · 2021 to 2024
$2.5M
Neonatal gut-on-a-chip platform for high content drug testing and precision medicineR01HD105301 · NICHD · WASHINGTON UNIVERSITY · PI GOOD, MISTY L, MAGNESS, SCOTT T · 2021 to 2024
$2.4M
Modulation of the Intestinal Immune Response in Necrotizing EnterocolitisR01DK118568 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2018 to 2022
$1.8M
Regulation of Intestinal Immunity by Aryl Hydrocarbon Receptor Signaling in Necrotizing EnterocolitisF32DK130248 · NIDDK · WASHINGTON UNIVERSITY · PI NOLAN, LILA · 2021 to 2022
$154k
NICHD NIH HHS R01 HD105301NIDDK NIH HHS F32 DK130248NIDDK NIH HHS R01 DK118568NIDDK NIH HHS R01 DK124614
6 · The paper itself

Abstract

Recapitulating human NEC using animal models has been insightful in dissecting the signaling pathways, immune-mediated mechanisms, genetic signatures, and the intestinal architecture of NEC. This protocol describes an

Indexed as

Disease Models, AnimalEnterocolitis, NecrotizingAnimalsAnimals, NewbornFecesHypoxiaIleumLipopolysaccharidesMiceLipopolysaccharidesDevelopmental biologyHealth SciencesMicrobiologyModel OrganismsMolecular Biology

Identifiers

PMID34816129
PMCPMC8593655
OpenAlexW3212574103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.