Evidence map›Paper›PMID 34816092›Full record

ArticleAccess microbiology2021

Photodynamic antimicrobial chemotherapy coupled with the use of the photosensitizers methylene blue and temoporfin as a potential novel treatment for

Alistair Hampden-Martin, Jo Fothergill, Mohamed El Mohtadi, Lucy Chambers, Anthony J Slate, Kathryn A Whitehead, Kayvan Shokrollahi

Open access · goldAbstract read
In one paragraph

Article in Access microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Targeted photodynamic neutralization of SARS-CoV-2 mediated by singlet oxygen.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Alistair Hampden-MartinFaculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Jo FothergillInstitute of Infection and Global Heath, University of Liverpool, Liverpool, UK.
Mohamed El MohtadiDepartment of Biology, Edge Hill University, Ormskirk, Lancashire, L39 4QP, UK.
Lucy ChambersMicrobiology at Interfaces, Manchester Metropolitan University, Manchester, UK.ORCID https://orcid.org/0000-0002-0626-095X
Anthony J SlateDepartment of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.ORCID https://orcid.org/0000-0002-7062-6901
Kathryn A WhiteheadMicrobiology at Interfaces, Manchester Metropolitan University, Manchester, UK.ORCID https://orcid.org/0000-0001-6001-6686
Kayvan ShokrollahiMersey Regional Burns and Plastic Surgery Unit, Whiston Hospital, Liverpool, UK.
Manchester Metropolitan University · GBUniversity of Liverpool · GBEdge Hill University · GBUniversity of Bath · GBWhiston Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic antimicrobial chemotherapy (PACT) is a novel alternative antimicrobial therapy that elicits a broad mechanism of action and therefore has a low probability of generating resistance. Such properties make PACT ideally suited for utilization in localized applications such as burn wounds. The aim of this study was to determine the antimicrobial activity of MB and temoporfin against both a

Indexed as

bacteriaburnsinfectionmethylene bluephotodynamic antimicrobial chemotherapytemoporfin

Identifiers

PMID34816092
PMCPMC8604179
OpenAlexW3210073357

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.