Evidence map›Paper›PMID 34815987›Full record

ArticleNeurobiology of stress2021

Dissection of the relationship between anxiety and stereotyped self-grooming using the

Haiying Liu, Xin Huang, Jinwei Xu, Honghui Mao, Yaohao Li, Keke Ren, Guaiguai Ma, Qian Xue, Huiren Tao, Shengxi Wu and 1 more

Abstract read
In one paragraph

Article in Neurobiology of stress, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Grooming as a window into the post-stress recuperative process.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Reproductive and immune-related consequences ofFrontiers in veterinary science · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Alpha-neurexins in health and disease.Frontiers in molecular neuroscience · 2025
    Review
  15. Article
  16. Article
  17. Hippocampal Engrams Generate Variable Behavioral Responses and Brain-Wide Network States.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haiying LiuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Xin HuangDepartment of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Jinwei XuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Honghui MaoDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Yaohao LiDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Keke RenDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Guaiguai MaDepartment of Physiology, Medicine College of Yan'an University, Yan'an, 716000, China.
Qian XueDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Huiren TaoDepartment of Spine Surgery, Shenzhen University General Hospital, Shenzhen, Guangdong, 518055, China.
Shengxi WuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.
Wenting WangDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-grooming is an innate, cephalo-caudal progression of body cleaning behaviors that are found in normal rodents but exhibit repetitive and stereotyped patterns in several mouse models, such as autism spectrum disorders (ASDs). It is also recognized as a marker of stress and anxiety. Mice with

Indexed as

AnxietyInflammatory painRestraintShank3Stereotyped self-grooming

Identifiers

PMID34815987
PMCPMC8591549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.