Evidence map›Paper›PMID 34815898›Full record

ArticleCureus2021

Non-surgical Management of Complex Refractory Pyoderma Gangrenosum With Negative Pressure Wound Therapy With Instillation.

Frank G Lee, Ethan Song, Sean J Wallace, Thomas J Shaughnessy, Mamtha Raj, Robert Teixeira, Marshall G Miles, Randolph Wojcik

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Frank G LeeDivision of Plastic and Reconstructive Surgery, University of South Florida Morsani College of Medicine, Tampa, USA.
Ethan SongDivision of Plastic and Reconstructive Surgery, University of South Florida Morsani College of Medicine, Tampa, USA.
Sean J WallaceDivision of Plastic and Reconstructive Surgery, Lehigh Valley Health Network, Allentown, USA.
Thomas J ShaughnessyDepartment of Physical Therapy and Wound Care, Lehigh Valley Health Network, Allentown, USA.
Mamtha RajDivision of Plastic and Reconstructive Surgery, Lehigh Valley Health Network, Allentown, USA.
Robert TeixeiraDivision of Plastic and Reconstructive Surgery, Lehigh Valley Health Network, Allentown, USA.
Marshall G MilesDivision of Plastic and Reconstructive Surgery, Lehigh Valley Health Network, Allentown, USA.
Randolph WojcikDivision of Plastic and Reconstructive Surgery, Lehigh Valley Health Network, Allentown, USA.
Lehigh Valley Hospital-Pocono · USLehigh Valley Health Network · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyoderma gangrenosum (PG) is a rare skin disorder primarily treated with immunosuppression medication. We report a case of a large, chronic PG wound treated with adjunct negative pressure wound therapy with instillation and dwell time (NPWTi-d) using nonadherent dressing (Mepitel) and reticular open-cell foam with through holes (ROCF-CC) with positive outcomes. The patient was a 62-year-old female with rheumatoid arthritis, Hashimoto's thyroiditis, lymphedema, and morbid obesity who presented with a 19.5 cm x 13.2 cm x 2.1 cm wound of three years duration on the right posterolateral lower extremity that successfully responded to a multimodality approach of immunosuppression and wound vac therapy. We conclude in our case that NPWTi-d with Mepitel and ROCF-CC enhanced the wound healing process, and we discuss NPWTi-d's potential role and benefit as an adjunctive therapy option for chronic and poorly controlled PG on patients taking concurrent immunosuppression.

Indexed as

instillationmepitelnegative pressure wound therapypyoderma gangrenosumrheumatoid arthritis

Identifiers

PMID34815898
PMCPMC8605928
OpenAlexW3209004065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.