ReviewCureus2021
Fournier's Gangrene Diagnosis and Treatment: A Systematic Review.
Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06809738 (Proposal for an Anatomical Scale for the Prognosis of Fournier Syndrome.), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Proposal for an Anatomical Scale for the Prognosis of Fournier Syndrome.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Hyperbaric oxygen therapy and Fournier's gangrene: a systematic review and meta-analysis.Medical gas research · 2026Pooled it
- Hyperbaric Oxygen Therapy Is Associated with Lower Mortality in Patients with Fournier's Gangrene: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Beyond Traditional Prognostic Scores: Associations of Organ Dysfunction and Metastatic Malignancy with Mortality in Fournier's Gangrene.Diseases (Basel, Switzerland) · 2026Article
- Clinical and laboratory predictors of mortality in Fournier's gangrene: prognostic role of the HALP score.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Article
- Fournier Gangrene in an Immunocompetent Woman Following Minor Perineal Manipulation: A Case Report.The American journal of case reports · 2026Article
- Şimşek Index (Kocaeli Fournier’s Gangrene Severity Index, KFGSI): Development and Prognostic Performance of an Admission-Based Mortality Prediction Model for Fournier’s GangreneUlusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Fournier's Gangrene and Purulent Peritonitis as a Result of Progressing Ischiorectal Abscess: A Case Report From Muhimbili National Hospital, Tanzania.Clinical case reports · 2026Article
- A new scoring system for the prediction of mortality in Fournier's gangrene: The Eğin score.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Penile squamous cell carcinoma masquerading as Fournier's Gangrene: A case of a young patient with aggressive, metastatic disease.Urology case reports · 2026Article
- Defining the Standard of Care in Fournier's Gangrene-An Umbrella Review.European urology open science · 2026Review
- Fulminant Fournier's gangrene following perineal trauma in a patient with suspected chronic inflammatory bowel disease: a case report.American journal of clinical and experimental urology · 2026Article
- Urogenital abscess with a complex etiology: a case report.AME case reports · 2026Article
- A Case Report of an Atypical Presentation of Fournier's Gangrene.Journal of education & teaching in emergency medicine · 2026Article
- The Usefulness of DEPAP Flaps for Reconstructing Perineal Defects Caused by Fournier's Gangrene: A Case Report.Journal of clinical medicine · 2025Article
- A Rare Case of Necrotizing Soft Tissue Infection in the Labium Resulting From Candida glabrata.Cureus · 2025Article
- Paediatric Fournier gangrene: comprehensive insights into diagnosis, management, and outcomes-a narrative review.Translational pediatrics · 2025Review
- The role of double-lumen irrigation-suction tube in the treatment of disseminated Fournier's gangrene: a single-center retrospective cohort study.Translational andrology and urology · 2025Article
- Modern Management of Fournier's Gangrene.Current urology reports · 2025Review
- Testicular ultrasound: an emergency medicine perspective.Internal and emergency medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fournier's gangrene (FG) is a perineal and abdominal necrotizing infection. It is most commonly found in middle-aged men with comorbidities such as diabetes mellitus. Initial symptoms are often indistinct and can rapidly progress to overwhelming infections with a relatively high mortality rate. It is crucial to make a prompt diagnosis so that the patient receives appropriate treatment. Given the importance of the identification of FG, we explored what were the most common signs and symptoms associated with FG, as well as distinguished the gold standard treatment. This systematic review utilized articles identified exclusively through PubMed using key terms such as Fournier's gangrene, signs, symptoms, and treatment. A total of 37 studies, including a total of 3,224 patients (3,093 males and 131 females), fit our inclusion parameters for relevance that included either the most identifiable presentation of FG or the most effective treatment. From our search, the most common clinical presentation was scrotal and labial pain, fever, abscesses, crepitus, erythema, and cellulitis. Diagnosis is made from clinical findings in conjunction with imaging. The gold standard for treatment was found to be a combination of surgical debridement, broad-spectrum antibiotics, and the administration of intravenous fluids. Further, patient survival was found to be directly related to the time from diagnosis to treatment when they underwent surgical debridement. The importance of early identification for improved outcomes or survival highlights the need for further studies or measures to enhance the identification of the signs and symptoms of FG.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.