Evidence map›Paper›PMID 34815798›Full record

ArticleTheranostics2021

Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.

Heng Sun, Jianming Zeng, Zhengqiang Miao, Kuan Cheok Lei, Chen Huang, Lingling Hu, Sek Man Su, Un In Chan, Kai Miao, Xu Zhang and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Aging-related genes related to the prognosis and the immune microenvironment of acute myeloid leukemia.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Heng SunCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Jianming ZengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Zhengqiang MiaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Kuan Cheok LeiCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Chen HuangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Lingling HuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Sek Man SuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Un In ChanCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Kai MiaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Xu ZhangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Aiping ZhangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Sen GuoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Si ChenCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Ya MengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Min DengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Wenhui HaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Haipeng LeiCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Ying LinBreast Disease Center, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhonglin YangZhuhai SanMed Biotech Ltd, Zhuhai, China.
Dongjiang TangZhuhai SanMed Biotech Ltd, Zhuhai, China.
Koon Ho WongCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Xiaohua Douglas ZhangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Xiaoling XuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Chu-Xia DengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBRCA1 ProteinBreastBreast NeoplasmsCarcinogenesisCell Line, TumorCell ProliferationCell Transformation, NeoplasticDNA RepairEpithelial-Mesenchymal TransitionFemaleGene ExpressionGene Expression ProfilingGene Expression Regulation, NeoplasticGenes, BRCA1Genetic HeterogeneityBRCA1 ProteinBrca1 protein, mouseBrca1/BRCA1mammary tumorMrc2single cell RNA-seqtumor heterogeneity

Identifiers

PMID34815798
PMCPMC8581428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.