ArticleTheranostics2021
Osteoblast-derived EGFL6 couples angiogenesis to osteogenesis during bone repair.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 45 citations in OpenAlex.
- OXR1 is a dual redox-mitochondrial checkpoint governing osteoclast differentiation and bone loss in an osteoporosis mouse model.Nature communications · 2026Article
- Blood and lymphatic vascular network in bone injury repair: from molecular mechanisms to therapeutic strategies.Science China. Life sciences · 2026Review
- EGFL6 predicts unfavorable prognosis and serves as a potential indicator in esophageal carcinoma.Discover oncology · 2026Article
- Designed bone-targeting ROS-responsive nanoplatform for precision glycolysis inhibition in postmenopausal osteoporosis.Bioactive materials · 2026Article
- Endothelial diversity in bone vasculature coordinates osteogenesis and hematopoiesis.Journal of bone and mineral metabolism · 2026Review
- Exosome-enabled bone defect repair: mechanistic foundations, bioengineered delivery, and artificial intelligence-driven translation.Journal of nanobiotechnology · 2026Review
- Nanozymes for Bone Regeneration: Mechanistic Insights into Immune and Metabolic Microenvironment Modulation.International journal of nanomedicine · 2026Review
- Bibliometric and Visual Analysis of the Global Research Status and Frontiers of Inflammation in Osteoporosis from 2000 to 2024.Indian journal of orthopaedics · 2025Article
- The Expression and Molecular Roles of MAMDC2 in MSS Colorectal Cancer with a High Tumor Stromal Ratio.Biomedicines · 2025Article
- Targeting type H vessels with bioactive metabolites from traditional Chinese botanical drugs: a therapeutic strategy for skeletal disorders.Frontiers in pharmacology · 2025Review
- Exploring the frontiers: The potential and challenges of bioactive scaffolds in osteosarcoma treatment and bone regeneration.Materials today. Bio · 2024Review
- Egfl6 promotes ovarian cancer progression by enhancing the immunosuppressive functions of tumor-associated myeloid cells.The Journal of clinical investigation · 2024Article
- EGFL6 activates the ERK signaling to improve angiogenesis and osteogenesis of BMSCs in patients with steroid-induced osteonecrosis of the femoral head.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice.Nature communications · 2024Article
- Cascaded controlled delivering growth factors to build vascularized and osteogenic microenvironment for bone regeneration.Materials today. Bio · 2024Article
- Targeting type H vessels in bone-related diseases.Journal of cellular and molecular medicine · 2024Review
- Photobiomodulation therapy's impact on angiogenesis and osteogenesis in orthodontic tooth movement: in vitro and in vivo study.BMC oral health · 2024Article
- The Paracrine Effect of Hyaluronic Acid-Treated Endothelial Cells Promotes BMP-2-Mediated Osteogenesis.Bioengineering (Basel, Switzerland) · 2023Article
- [Regulation of non-coding RNA in type H vessels angiogenesis of bone].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Article
- EGFL7 Secreted By Human Bone Mesenchymal Stem Cells Promotes Osteoblast Differentiation Partly Via Downregulation Of Notch1-Hes1 Signaling Pathway.Stem cell reviews and reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 4 institutions in 3 countries.
Kai ChenSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Shijie LiaoSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Yicheng LiGuangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Haibo JiangSchool of Molecular Sciences, University of Western Australia, Perth, WA, Australia.
Yun LiuSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Chao WangSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Vincent KuekSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Jacob KennySchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Boxiang LiDepartment of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Qian HuangDepartment of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jianxin HongWenzhou Medical University, Wenzhou, Zhejiang, China.
Yan HuangShanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shek Man ChimSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Jennifer TicknerSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Nathan J PavlosSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Jinmin ZhaoGuangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Qian LiuSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
An QinShanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiake XuSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
University of Western Australia · AUGuangxi Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CNWenzhou Medical University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsBone and BonesBone Marrow CellsBone Morphogenetic ProteinsBone RegenerationCalcium-Binding ProteinsCell Adhesion MoleculesCell DifferentiationCell LineFemaleMaleMAP Kinase Signaling SystemMesenchymal Stem CellsMiceMice, Inbred C57BLNeovascularization, PhysiologicBone Morphogenetic ProteinsCalcium-Binding ProteinsCell Adhesion MoleculesEgfl6 protein, mouseSmad Proteinsangiogenesisbone defectbone repairEGFL6osteogenesis
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.